Supercritical fluid chromatography: A technology update

Gere, Dennis R.; Houck, Raymond K.; Pacholec, F.; Rosselli, A. C.

doi:10.1007/bf00515610

Cited by 5 publications

(2 citation statements)

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“…This method was further developed theoretically as well as experimentally by other workers in 1960s. At the Pittsburgh Conference 1981-1982, HewlettPackard introduced SFC instrumentation for packed columns where Dennis R. Gere and his associates at Hewlett-Packard modified a commercial HPLC instrument for supercritical fluid chromatography (Gere et al 1988). They used 10 cm × 4.6 mm i.d.…”

Section: History Of Development Of Supercritical Fluid Chromatographymentioning

confidence: 99%

Supercritical Fluid Chromatography: A Green Approach for Separation and Purification of Organic and Inorganic Analytes

Datta

Auddy

2013

Green Chromatographic Techniques

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'Supercritical fluid' describes a gas or liquid at conditions above its critical point. A greater range of solvent properties can be achieved with Supercritical fluid as a single solvent by careful manipulation of temperature and pressure at the supercritical state. Supercritical fluids are attractive media for several chemical reactions having better control over the reaction rates in different areas of biochemistry, polymer chemistry and environmental science. Supercritical fluid extraction (SFE), a rapid, convenient, efficient, and selective method has been used successfully for the separation of analytes prior to supercritical fluid chromatography (SFC), which is a relatively recent chromatographic technique and is commercially available since 1982. SFC significantly reduces the usage of organic solvents and wastes by using supercritical CO 2 as the mobile phase. The important principles of green chemistry that are applicable to green chromatography includes prevention of waste, use of safer solvents and increasing energy efficiency. All these factors are taken care of in SFC which combines some of the best features of HPLC as well as GC. Analytes that cannot be vaporized for analysis by gas chromatography or have no functional groups for detection by the usual liquid chromatography techniques, can be separated and detected using SFC. By now SFC has been applied to wide variety of materials including natural products, pharmaceuticals, foods, pesticides, herbicides, surfactants, polymers and polymer additives, heavy metals, fossils fuels, petroleum, explosives and propellants. SFC has now become an attractive alternative for chiral drug separation.

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Section: History Of Development Of Supercritical Fluid Chromatographymentioning

confidence: 99%

Supercritical Fluid Chromatography: A Green Approach for Separation and Purification of Organic and Inorganic Analytes

Datta

Auddy

2013

Green Chromatographic Techniques

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“…The emerging of supercritical fluid chromatography (SFC) in separation science has grown rapidly in recent years. The unique properties of supercritical fluid as mobile phase in SFC overcome the difficulties of solute thermal instability and volatility encountered in GC and also shorten the relatively longer analyses times of HPLC separations [1]- [5]. Although GC and HPLC are good separating tools in their own ways, the SFC is a more powerful technique in comparison.…”

Section: Introductionmentioning

confidence: 99%

Packed Supercritical Fluid Chromatography for the Analyses and Preparative Separations of Palm Oil Minor Components

Ng¹,

Choo²

2015

AJAC

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This paper depicts a brief review on the applications of packed supercritical fluid chromatography (SFC) in palm oil analyses and purifications from early 1990s to date. Packed SFC has been used for the analyses of various palm oil components. The analytical separations have also been scaled up to preparative scale that leads to the recovery of high value components from palm oil. This review encompasses both analytical and preparative SFC in the oil palm processing.

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Quantification of Retinoid Compounds by Supercritical Fluid Chromatography Coupled to Ultraviolet Diode Array Detection

et al. 2013

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Supercritical fluid chromatography: A technology update

Cited by 5 publications

References 0 publications

Supercritical Fluid Chromatography: A Green Approach for Separation and Purification of Organic and Inorganic Analytes

Supercritical Fluid Chromatography: A Green Approach for Separation and Purification of Organic and Inorganic Analytes

Packed Supercritical Fluid Chromatography for the Analyses and Preparative Separations of Palm Oil Minor Components

Quantification of Retinoid Compounds by Supercritical Fluid Chromatography Coupled to Ultraviolet Diode Array Detection

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