“…The operational conditions for the first extraction step with supercritical CO 2 (ScCO 2 ) were established with the purpose of obtaining high extraction yields and concentrated extracts in polyphenols substances according to as reported in previous experimental works (Garmus et al, 2014;Prado, Prado, Prado, & Meireles, 2013). Additionally, due to the fact that supercritical extraction yields are benefited by the increase of density of the solvent and the vapor pressure of the solute as reported by Moura, Prado, Meireles, and Pereira (2012), who obtained high extraction yield at 30 MPa and temperatures between 35 C and 55 C. It was presumed that extraction at 30 MPa/40 C would be ideal for supercritical extraction of mango peel.…”