2015
DOI: 10.1016/j.supflu.2015.03.005
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Supercritical carbon dioxide extraction of glycyrrhizic acid from licorice plant root using binary entrainer: Experimental optimization via response surface methodology

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Cited by 50 publications
(20 citation statements)
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“…The extraction of glycyrrhizic acid from licorice by the conventional liquid–liquid extraction technique is characterized by several disadvantages, such as high extraction times and temperatures, large solvent requirements, and low yields. Macroporous resins [8], ultrasound-estraction [9], microwave-assisted extraction [10], supercritical CO 2 extraction [11], high-speed [12], and pH-zone-refining counter-current chromatography [13] have also been adopted. However, most of these procedures involve a number of steps and large amounts of solvent/chemicals; additional disadvantages include poor recovery (from 20% to 30%) and high process costs.…”
Section: Introductionmentioning
confidence: 99%
“…The extraction of glycyrrhizic acid from licorice by the conventional liquid–liquid extraction technique is characterized by several disadvantages, such as high extraction times and temperatures, large solvent requirements, and low yields. Macroporous resins [8], ultrasound-estraction [9], microwave-assisted extraction [10], supercritical CO 2 extraction [11], high-speed [12], and pH-zone-refining counter-current chromatography [13] have also been adopted. However, most of these procedures involve a number of steps and large amounts of solvent/chemicals; additional disadvantages include poor recovery (from 20% to 30%) and high process costs.…”
Section: Introductionmentioning
confidence: 99%
“…Recently, Hedayati and Ghoreishi () evaluated the effect of different process parameters on the recovery of glycyrrhizin from licorice. Their results showed that increasing pressure favored the recovery of glycyrrhizin while the solubility and extraction of glycyrrhizin increased as a function of density.…”
Section: Resultsmentioning
confidence: 99%
“…The objective is to understand the interaction among various parameters and the optimization of the operating conditions to obtain the best response, simultaneously 19 . RSM is a useful tool which has been widely applied successfully in several fields for the optimization of operating parameters in various processes [20][21][22] .…”
Section: Fig 4: the Flow Sheet Of The Electrothermal Fluidized Bed Cmentioning
confidence: 99%