Super High Dosing with a Novel Buttiauxella Phytase Continuously Improves Growth Performance, Nutrient Digestibility, and Mineral Status of Weaned Pigs

Zeng, Zhikai; Li, Qingyun; Tian, Qiyu; Zhao, Panfeng; Xu, Xiao; Yu, Shukun; Piao, Xiangshu

doi:10.1007/s12011-015-0319-2

Cited by 29 publications

(30 citation statements)

References 28 publications

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“…As expected, pigs fed the NC diet with reduced P, Ca and ME had lower ADFI, ADG and G:F compared with those receiving the PC, which is in agreement with many previous studies ( Kies et al., 2006 , Zeng et al., 2015 ).…”

Section: Discussionsupporting

confidence: 93%

“…Recently, new phytase enzymes have been produced, including a Buttiauxella sp. phytase that are more efficacious in improving total tract P digestion and conferred additional benefits at dose rates above 500 FTU/kg ( Bento et al., 2012 , Zeng et al., 2015 ). Trials with broiler chickens noted a higher efficacy of Buttiauxella phytase when compared with Escherichia coli phytases ( Kumar et al., 2012 ).…”

Section: Introductionmentioning

confidence: 99%

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Productive performance of commercial growing and finishing pigs supplemented with a Buttiauxella phytase as a total replacement of inorganic phosphate

et al. 2018

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The objective of this study was to test if a novel phytase from Buttiauxella sp. can replace all added inorganic phosphate in a diet with reduced Ca and metabolizable energy (ME) fed to commercial pigs from 12 kg body weight (BW) until slaughter, whilst maintaining performance and carcass quality parameters. Four dietary treatments were tested in a completely randomized design with 9 replicate pens, each containing 31 mixed sex Newsham Choice pigs. Diets included a positive control (PC) based on corn, soybean meal, wheat middling and bakery meal, meeting all nutrient requirement of pigs; a negative control (NC) excluded inorganic phosphate and with reduced Ca (−0.13%) and ME (−0.15 MJ/kg); and NC supplemented with Buttiauxella phytase at 500 or 1,000 FTU/kg feed. Diets were fed ad libitum in mash form in 5 phases: starter (12 to 25 kg BW), grower 1 (25 to 50 kg BW) and 2 (50 to 75 kg BW), and finisher 1 (75 to 100 kg BW) and 2 (100 kg BW to slaughter). The NC group showed lower (P < 0.05) average daily feed intake (ADFI) and average daily gain (ADG) in starter and grower phases, lower gain to feed ratio (G:F) in starter and grower 1 compared with PC. Pigs receiving the high dose of phytase of 1,000 FTU/kg had improved performance vs. the 500 FTU/kg phytase treatment in starter and grower 1 phase compared with the PC in grower 1 phase. Increasing phytase dose resulted in a linear increase in ADG (12 to 120 kg BW) and G:F (50 to 75 kg BW). A comparison of treatment groups over the full production period from 12 kg BW until slaughter showed that both 500 and 1,000 FTU/kg phytase treatments were able to maintain growth performance and carcass characteristics compared with PC. The application of Buttiauxella phytase could therefore be used as an effective strategy to replace all inorganic phosphate in diets of pigs fed corn, soybean meal, wheat middling and bakery meal based diets from 12 kg BW. An economic analysis showed greater return from both phytase treatments vs. the PC and favored the higher phytase dose at 1,000 FTU/kg vs. the traditional dose of 500 FTU/kg. The latter was mainly related to the improved performance of the higher dose in younger pigs to 75 kg BW.

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Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Productive performance of commercial growing and finishing pigs supplemented with a Buttiauxella phytase as a total replacement of inorganic phosphate

et al. 2018

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“…For the first time, here we show that the negative outcome of protein-deficient diets on daily weight gain, final body weight and protein efficiency ratio of pigs is alleviated when these diets are supplemented with a CEP with no adverse effects of reduced dietary Ca and P. Similar positive effects for microbial phytase [ 20 , 21 , 22 , 23 , 24 , 25 ] and a CEP [ 34 , 35 ] were reported in the nursery, growing and finisher pigs fed with adequate protein but Ca and P deficient diets. The beneficial effect of CEP on the growth performance of pigs in both Ca and P adequate and deficient diets might be due to improvement in the utilization of Ca, P, and other nutrients [ 34 , 35 ].…”

Section: Discussionmentioning

confidence: 81%

“…The most common type of exogenous phytase used in the swine diet is microbial phytase. There is a plethora of evidence that digestibility and utilization of P and Ca are increased in pigs when microbial phytase was supplemented in their diets formulated with adequate Ca and P [ 16 , 17 , 18 , 19 ] or reduced Ca- and P [ 20 , 21 , 22 , 23 , 24 , 25 ]. However, there are conflicting reports on the effects of microbial phytase on the digestibility of N and amino acids in pigs [ 26 , 27 ].…”

Section: Introductionmentioning

confidence: 99%

A Novel Corn-Expressed Phytase Improves Daily Weight Gain, Protein Efficiency Ratio and Nutrients Digestibility and Alters Fecal Microbiota in Pigs Fed with Very Low Protein Diets

Shili

Broomhead

Spring

et al. 2020

Animals

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The objective of this study was to assess the effect of a novel corn-expressed phytase (CEP) on growth, nutrients digestibility, bone characteristics and fecal microbiota of pigs fed with very low-protein, -calcium (Ca) and -phosphorous (P) diets. Forty-eight barrows were subjected to 6 groups for 4 weeks: positive control-adequate protein (PC), negative control-reduced protein (NC), NC + low-dose CEP, i.e., 2000 FTU/kg (LD), NC + high-dose CEP, i.e., 4000 FTU/kg (HD), LD with 0.12% unit reduced Ca and 0.15% unit reduced available P (LDR), and HD with 0.12% unit reduced Ca and 0.15% unit reduced available P (HDR). Compared to NC, LD and HDR had a higher average daily gain (ADG) and gain:protein ratio (G:P), HD and HDR had greater apparent fecal digestibility of Ca and P and bone mineral density and LDR and HDR had lower serum osteocalcin. The feces of LD was enriched in Lachnospiraceae, while the HD had a higher abundance of Succinvibrio and LDR had a higher abundance of Bifidobacterium and Actinobacteria. In conclusion, supplementation of protein-restricted diets with a CEP decreased their negative effects on ADG and G:P ratio, increased the digestibility of Ca and P regardless of the levels of these minerals in the diet, improved bone characteristics and produced differential effects on fecal bacterial population.

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“…2 No data available for cells containing "-". ◊ ity over and above the expected improvements in P and Ca (Adedokun et al, 2015;Zeng et al, 2015), and this, combined with the differential pH optimum of Buttiauxella sp. phytase, which allows for nutrient release higher in the digestive tract (Menezes-Blackburn et al, 2015), will contribute to the reduction in weight loss demonstrated in this study.…”

Section: Discussionmentioning

confidence: 91%

The addition of a Buttiauxella sp. phytase to lactating sow diets deficient in phosphorus and calcium reduces weight loss and improves nutrient digestibility

Wealleans

Bold

Dersjant-Li

et al. 2015

Journal of Animal Science

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Improving the efficiency of P use by pigs is especially important for lactating sows, whose metabolic requirements for P and Ca are high. The effect of a sp. phytase on lactating sow performance and nutrient digestibility was investigated using the combined data set for 6 studies. Treatments included a nutritionally adequate positive control diet (PC), a negative control diet (NC; with an average reduction of 0.16% available phosphorous and 0.15% Ca vs. PC), and NC supplemented with a sp. phytase at 250, 500, 1,000 or 2,000 phytase unit (FTU)/kg, respectively. Phosphorus and Ca deficiency in the NC resulted in significantly higher BW loss compared with the PC. All phytase treatments maintained BW loss at the same level as the PC. Increasing doses of phytase significantly ( < 0.05) reduced sow BW loss and increased energy intake, with improvements most apparent in sows older than parity 5. The positive effects on BW and energy intake were not observed in first-parity sows. This may be a consequence of fewer first parity sows in the data set. The apparent total tract digestibility of DM, OM, and CP were not affected by phytase supplementation. Digestible P and Ca were significantly improved (linear, < 0.0001; quadratic, < 0.0001) by increasing the dose of phytase supplementation. Significantly lower apparent total tract digestibility of energy, Ca, and P was found in the NC treatment vs. the PC treatment, whereas no significant differences were found between phytase treatment and the PC treatment. In conclusion, phytase supplementation at a level of 250 FTU/kg can replace 0.16% available phosphorous and 0.15% Ca; however, increasing the phytase dose can further reduce BW loss in sows fed P- and Ca- deficient diets.

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Super High Dosing with a Novel Buttiauxella Phytase Continuously Improves Growth Performance, Nutrient Digestibility, and Mineral Status of Weaned Pigs

Cited by 29 publications

References 28 publications

Productive performance of commercial growing and finishing pigs supplemented with a Buttiauxella phytase as a total replacement of inorganic phosphate

Productive performance of commercial growing and finishing pigs supplemented with a Buttiauxella phytase as a total replacement of inorganic phosphate

A Novel Corn-Expressed Phytase Improves Daily Weight Gain, Protein Efficiency Ratio and Nutrients Digestibility and Alters Fecal Microbiota in Pigs Fed with Very Low Protein Diets

The addition of a Buttiauxella sp. phytase to lactating sow diets deficient in phosphorus and calcium reduces weight loss and improves nutrient digestibility

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