Sulfonamide Vasculitis<sup>1</sup>

Lehr, David

doi:10.1002/j.1552-4604.1972.tb00159.x

Cited by 3 publications

(2 citation statements)

References 9 publications

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“…There are also indirect effects, based on immunological reactions, which appear with a variable delay. There are several other examples, where different types of mechanisms cause neuropathy: immune checkpoint inhibitors (ICI), where an autoimmune mechanism is activated, sulfonamides that rarely induce vasculitis-causing neuropathy [ 28 ], aerosols that can induce Guillain–Barrè syndrome (GBS) in swine abattoir workers [ 29 ] as well as the Spanish toxic oil syndrome, probably causing vasculitis [ 30 ], or the toxic gold treatments in rheumatology [ 31 ].…”

Section: Clinical Features Of Tnsmentioning

confidence: 99%

Toxicity in Peripheral Nerves: An Overview

Grisold

Carozzi

2021

Toxics

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Introduction to a collection. This article is intended to introduce a collection of papers on toxic neuropathies. Toxic neuropathies can be caused by a variety of substances and by different mechanisms. Toxic agents are numerous and can be distinguished between drugs, recreational agents, heavy metals, industrial agents, pesticides, warfare agents, biologic substances and venoms. Toxic agents reach the nervous system by ingestion, transcutaneously, via the mucous membranes, parenterally and by aerosols. The most frequent types are cumulative toxicities. Other types are acute or delayed toxicities. Pathogenetic mechanisms range from a specific toxic substance profile causing axonal or demyelinating lesions, towards ion channel interferences, immune-mediated mechanisms and a number of different molecular pathways. In addition, demyelination, focal lesions and small fiber damage may occur. Clinically, neurotoxicity presents most frequently as axonal symmetric neuropathies. In this work, we present a panoramic view of toxic neuropathy, in terms of symptoms, causes, mechanisms and classification.

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Section: Clinical Features Of Tnsmentioning

confidence: 99%

Toxicity in Peripheral Nerves: An Overview

Grisold

Carozzi

2021

Toxics

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“…A review of hypersensitivity reaotis to sulphonamides showed that increasing dosage led to a greater frequency of sensitization reactions. It was concluded that the sensiting dose may constitute the trigger which sets the disease process in motion in the susceptible patient (Lehr, 1972).…”

Section: Discussionmentioning

confidence: 99%