Sulcus fluid volume, IL‐6, and Il‐1b concentrations in periodontal and peri‐implant tissues comparing machined and laser‐microtextured collar/abutment surfaces during 12 weeks of healing: A split‐mouth RCT

Abstract

Objectives: To compare gingival tissue healing at surgically manipulated periodontal sites and at sites receiving implants and healing abutments with machined (MS) vs laser-microtextured (LMS) surface placed with one-stage protocol.Material and Methods: Twenty-four non-smoking patients each received two implants with one-stage protocol in a split-mouth design on the same jaw. In each patient, one implant with a MS collar and one immediate healing abutment with a MS, and one implant with a LMS collar and one immediate healing abutment with a LMS were used. Soft tissues healing at surgically manipulated periodontal tissues (T+) and at non-surgically manipulated periodontal tissues (T-) at MS implant sites and at LMS implant sites were compared by means of clinical and biochemical parameters at baseline and at 1-2-3-4-6-8 and 12 weeks.Results: PD and BoP mean values were statistically higher in MS than LMS implant sites (p<0.05). During early healing phase (1-4 weeks), MS and LMS peri-implant tissues and periodontal tissues at T(+) showed no statistically significant difference in crevicular fluid volume changes (p>0.05). Between 6 and 12 weeks, compared with T(+), no statistically significant difference in crevicular fluid volume and IL-6 and IL-1β concentrations was noted in LMS implant sites (p>0.05), while statistically significantly higher mean values were noted in MS implant sites (p<0.05).Conclusions: Compared with T(+) and T(-), both MS and LMS implant sites presented a higher pro-inflammatory state in the early phase after surgery (1-4 weeks). At 12 weeks, only MS implant sites kept a higher pro-inflammatory state, while at LMS implant sites, it becomes similar to T(+) and T(-).

Survival and Success Rates of Monolithic Zirconia Restorations Supported by Teeth and Implants in Bruxer versus Non-Bruxer Patients: A Retrospective Study

“…Because of the small sample size of implants in the current study, the difference between the survival of implants with either cemented or screw-retained restorations could not be analyzed. The type of restoration can affect the stability of the peri-implant tissues, regardless of the occlusal load [24].…”

A Systematic Review of Cementation Techniques to Minimize Cement Excess in Cement-Retained Implant Restorations

“…This conclusion, however, finds a further explanation in the rather short follow-up studies on more numerous samples and with 10-year follow-up studies, all of which have revealed high levels of inflammation. Specifically, this assessment must be noted for the results of the study by Kiran et al, which are also justifiable for short follow-ups [ 33 , 34 , 35 ].…”

In Silico Novel Drug Design Targeting the Oral Microbiome: Endodontic and Periodontal Pathogenic Bacteria

“…Additionally, it is important to remember that many bacterial species are found in saliva, gingival crevice fluid, and colonizing soft tissues such as the back of the tongue and tonsils. The different compositions of these fluids, depending on their constituents, can significantly change the number of bacteria present and their ability to replicate [1].…”

“…Subsequently, better understanding the mechanisms underlying the modifications of endogenous secretions and endogenous molecules is necessary, with increasing attention on psycho-neuro-immuno-endocrine correlations [1,[3][4][5].…”

“…Considering the rich presence of fluids in periodontal tissues and how they offer substrates and nutrients to bacteria, it is of fundamental importance to understand these aspects and to evaluate the possibility of conveying molecules and drugs that can improve tissue health through these fluids [1,5,9]. The evaluation of the characteristics of bacteria that cause endodontic alterations is also fundamental [10].…”