Suicidal risk, affective dysphoric disorders, and quality-of-life perception in patients with focal refractory epilepsy

Andrade-Machado, René; Ochoa-Urrea, Manuela; García-Espinosa, A; Benjumea-Cuartas, Vanessa; Santos-Santos, Aisel

doi:10.1016/j.yebeh.2015.01.005

Cited by 27 publications

(22 citation statements)

References 45 publications

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“…Trigeminal neuralgia also has a known association with depression, anxiety and sleep disorders 13. Furthermore, epilepsy is also associated with psychiatric comorbidities and risk of suicide 14. Thus, it is not inconceivable that these conditions, when refractory to treatment, can cause a significant decline in the quality of life and prompt some patients to request MAID.…”

Section: Discussionmentioning

confidence: 99%

Canadian neurosurgeons’ views on medical assistance in dying (MAID): a cross-sectional survey of Canadian Neurosurgical Society (CNSS) members

et al. 2019

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BackgroundThe Supreme Court of Canada removed the prohibition on physicians assisting in patients dying on 6 February 2015. Bill C-14, legalising medical assistance in dying (MAID) in Canada, was subsequently passed by the House of Commons and the Senate on 17 June 2016. As this remains a divisive issue for physicians, the Canadian Neurosurgical Society (CNSS) has recently published a position statement on MAID.MethodsWe conducted a cross-sectional survey to understand the views and perceptions among CNSS members regarding MAID to inform its position statement on the issue. Data was collected from May to June 2016.ResultsOf the 300 active membes of the CNSS who recevied the survey, 89 respondents completed the survey, 71% of whom were attending neurosurgeons and 29% were neurosurgery residents. Most respondents,74.2%, supported the right of physicians to participate in MAID with 7.8% opposing. 37% had current patients in their practice fitting the criteria for MAID. 23.6% had been asked by patients to assist with MAID, but only 11% would consider personally providing it. 84% of neurosurgeons surveyed supported the physicians’ right to conscientious objection to MAID while 21% thought attending surgeons should be removed from the inquiry and decision-making process. 43.8% agreed that the requirment to refer a patient to a MAID service should be mandatory. Glioblastoma multiforme (65%), quadriplegia/quadriparesis secondary to spinal tumour/trauma (54%) and Parkinson’s disease (24%) were the most common suggested potential indications for MAID among the neurosurgical population.ConclusionsOur results demonstrate that most neurosurgeons in Canada are generally supportive of MAID in select patients. However, they also strongly support the physicians’ right to conscientious objection.

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Section: Discussionmentioning

confidence: 99%

Canadian neurosurgeons’ views on medical assistance in dying (MAID): a cross-sectional survey of Canadian Neurosurgical Society (CNSS) members

et al. 2019

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“…22-25 We found much higher odds of hospitalization for suicide attempt/ideation, and prolonged LOS for suicide related admissions in CWE. Previous studies have attributed an increased risk in suicidality in person with epilepsy to multiple psychiatric conditions, including depression, psychosis and mania.…”

Section: Discussionmentioning

confidence: 75%

Hospital care for mental health and substance abuse in children with epilepsy

Thibault

Mendizabal

Abend

et al. 2016

Epilepsy & Behavior

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Background Reducing the burden of pediatric mental illness requires greater knowledge of Mental Health and Substance Abuse (MHSA) outcomes in children who are at an increased risk of primary psychiatric illness. National data on hospital care for psychiatric illness in children with epilepsy are limited. Methods We used the Kids’ Inpatient Database (KID), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality, from 2003-2009 to examine MHSA hospitalization patterns in children with comorbid epilepsy. Non-parametric and regression analyses determined the association of comorbid epilepsy with specific MHSA diagnoses and examined the impact of epilepsy on length of stay (LOS) for such MHSA diagnoses while controlling for demographic, payer and hospital characteristics. Results We observed 353,319 weighted MHSA hospitalizations of children ages 6 - 20; 3,280 of these involved a child with epilepsy. Depression was the most common MHSA diagnosis in the general population (39.5%) whereas bipolar disorder was the most common MHSA diagnosis among children with epilepsy (36.2%). Multivariate logistic regression models revealed that children with comorbid epilepsy had greater adjusted odds of bipolar disorder (AOR 1.17, 1.04-1.30), psychosis (AOR 1.78, 1.51-2.09), sleep disorder (AOR 5.90, 1.90-18.34), and suicide attempt/ ideation (AOR 3.20, 1.46-6.99) compared to the general MHSA inpatient population. Epilepsy was associated with a greater LOS and a higher adjusted incidence rate ratio (IRR) for prolonged LOS (IRR 1.12, 1.09-1.17), particularly for suicide attempt/ideation (IRR 3.74, 1.68-8.34). Conclusions Children with epilepsy have distinct patterns of hospital care for mental illness and substance abuse, and experience prolonged hospitalization for MHSA conditions. Strategies to reduce psychiatric hospitalizations in this population may require disease specific approaches and should measure disease relevant outcomes. Hospitals caring for large numbers of children with neurological disease (such as academic centers) may have inaccurate measurements of mental health care quality unless the impact of key comorbid conditions such as epilepsy is considered.

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“…Межприступное дисфори-ческое расстройство включает в себя многие черты, харак-терные (по DSM IV критериям) для депрессии, но с «добав-лением эйфории» [20]. Рассматривая связь суицидальной активности с дисфорическими расстройствами и качеством жизни больных эпилепсией на основании обследования 82 больных, были сделаны выводы о том, что наибольшая суи-цидальная активность отмечается у 40,5% больных височ-ной эпилепсией при наличии более чем в половине случа-ев (52%) в картине болезни «аффективного соматоформно-го дисфорического расстройства» [21].…”

Section: типология аффективных расстройств при эпилепсииunclassified

Phenomenology and Therapy of Affective Disorders in Epilepsia

Усюкина¹

2018

Med. sov.

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Suicidal risk, affective dysphoric disorders, and quality-of-life perception in patients with focal refractory epilepsy

Cited by 27 publications

References 45 publications

Canadian neurosurgeons’ views on medical assistance in dying (MAID): a cross-sectional survey of Canadian Neurosurgical Society (CNSS) members

Canadian neurosurgeons’ views on medical assistance in dying (MAID): a cross-sectional survey of Canadian Neurosurgical Society (CNSS) members

Hospital care for mental health and substance abuse in children with epilepsy

Phenomenology and Therapy of Affective Disorders in Epilepsia

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