Suicidal Ideation in Inpatients with Acute Schizophrenia

Kontaxakis, V.P.; Havaki-Kontaxaki, B.J.; Margariti, Maria; Stamouli, S.S.; Kollias, C.T.; Christodoulou, George N.

doi:10.1177/070674370404900709

Cited by 54 publications

(42 citation statements)

References 18 publications

(11 reference statements)

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“…Suicidal ideation, however, was not associated with violence in either this study or in a previous meta-analysis of risk factors for violence in psychosis (Witt et al, 2013). One reason may be that suicidal ideation is extremely common in this population (Kontaxakis et al, 2004). Alternatively it may be that while violence is associated with more behavioral forms of suicidality, such as attempted suicide, it is not related to suicidal ideation, as has previously been shown in prisoner populations (Sarchiapone et al, 2009; Zhang et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

The relationship between suicide and violence in schizophrenia: Analysis of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) dataset

Witt

Hawton

Fazel

2014

Schizophrenia Research

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BackgroundSuicide and violence often co-occur in the general population as well as in mentally ill individuals. Few studies, however, have assessed whether these suicidal behaviors are predictive of violence risk in mental illness.AimsThe aim of this study is to investigate whether suicidal behaviors, including suicidal ideation, threats, and attempts, are significantly associated with increased violence risk in individuals with schizophrenia.MethodData for these analyses were obtained from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) trial, a randomized controlled trial of antipsychotic medication in 1460 adults with schizophrenia. Univariate Cox regression analyses were used to calculate hazard ratios (HRs) for suicidal ideation, threats, and attempts. Multivariate analyses were conducted to adjust for common confounding factors, including: age, alcohol or drug misuse, major depression, antisocial personality disorder, depression, hostility, positive symptom, and poor impulse control scores. Tests of discrimination, calibration, and reclassification assessed the incremental predictive validity of suicidal behaviors for the prediction of violence risk.ResultsSuicidal threats and attempts were significantly associated with violence in both males and females with schizophrenia with little change following adjustment for common confounders. Only suicidal threats, however, were associated with a significant increase in incremental validity beyond age, diagnosis with a comorbid substance use disorder, and recent violent behavior.ConclusionsSuicidal threats are independently associated with violence risk in both males and females with schizophrenia, and may improve violence risk prediction.

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Section: Discussionmentioning

confidence: 99%

The relationship between suicide and violence in schizophrenia: Analysis of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) dataset

Witt

Hawton

Fazel

2014

Schizophrenia Research

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“…Numerous studies have identified associations between mental illnesses and low self-esteem. Most notable in this context is, of course, depression that, among other factors, is diagnosed on the basis of low feelings of self-worth, although several other mental health disorders have also been associated with the latter (see recent examples in e.g., Awad & Voruganti, 2004;Combs & Penn, 2004;Kontaxakis et al, 2004). As such, one might expect that borderline pathological celebrity worship, with its overtones of mental disorder, might be associated negatively with self-esteem.…”

Section: Self-esteemmentioning

confidence: 99%

Attributional Style, Self-Esteem, and Celebrity Worship

et al. 2007

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“…Identified correlates of SI in this population have included mood variability, negative symptoms, and depressive symptoms (Fialko et. al., 2006; Hocaoglu and Babuc, 2009; Jovanovic et al, 2013; Kontaxakis et al, 2004; Palmier-Claus et al, 2013), as well as positive symptoms (Taylor et al, 2010). We have previously examined the prevalence of SI in young people at clinical high-risk for psychosis (CHR), finding that 55% reported having suicidal thoughts (DeVylder et al, 2012), a prevalence replicated in other cohorts (Hutton et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Assessing suicidal ideation in individuals at clinical high risk for psychosis

Gill

Quintero

Poe

et al. 2015

Schizophrenia Research

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Background The majority of individuals with schizophrenia and other psychotic illnesses have had suicidal ideation at some point during the illness. However, little is known about the variation in level and intensity of suicidal ideation and symptoms in the attenuated stage of psychotic illness. Our aims were to assess prevalence of suicidal ideation in this at risk group, and to examine the severity and intensity of suicidal ideation, and their relation to symptoms. Methods Suicidal ideation was assessed in 42 clinical high-risk participants using the Columbia Suicide Severity Rating Scale (C-SSRS). We hypothesized prevalence rates would be similar to what was found in previous studies, and individuals with suicidal ideation would have higher positive and negative symptoms, with poorer functioning. We assessed levels of severity and intensity of suicidal ideation related to these symptoms, and examined how depressive symptoms affected these relationships. Results Nearly half (42.9%) of participants reported having current suicidal ideation. We found no relationship to positive symptoms. However, severity and intensity of suicidal ideation was found to be related to negative symptoms and level of functioning. When controlling for depressive symptoms during exploratory analysis, this relationship still emerged. Conclusions This study adds to the literature demonstrating the complex nature of suicidal ideation in psychotic illness. The C-SSRS has shown to be helpful in determining relationships between severity and intensity in suicidal ideation in relation to specific symptoms in a research setting.

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Suicidal Ideation in Inpatients with Acute Schizophrenia

Abstract: Suicidal thoughts are frequent among inpatients with acute schizophrenia. Prevention of suicidal behaviour should include helping patients improve their self-esteem and reducing depression and guilt feelings.

Cited by 54 publications

References 18 publications

The relationship between suicide and violence in schizophrenia: Analysis of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) dataset

The relationship between suicide and violence in schizophrenia: Analysis of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) dataset

Attributional Style, Self-Esteem, and Celebrity Worship

Assessing suicidal ideation in individuals at clinical high risk for psychosis

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