Sudden Deafness: Is It Viral?

Merchant, Saumil N.; Durand, Marlene L.; Adams, Joe C.

doi:10.1159/000111048

“…Different theories have been proposed to explain the etiology. These include, for example, bacterial, viral, and protozoan infections, vascular occlusion, mechanisms associated with the immune system, ototoxicity drugs (salicylates, aminoglycosides) and traumatic, vascular, neoplastic, and metabolic conditions [7][8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Mean Platelet Volume: Is It a Predictive Parameter in The Diagnosis of Sudden Sensorineural Hearing Loss?

Karli

¹

,

Alaçam

²

,

Ünal

³

et al. 2013

Indian J Otolaryngol Head Neck Surg

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The mean platelet volume (MPV) is associated with increased platelet reactivity and increased atherothrombosis. High MPV values are a risk factor for thrombotic vascular diseases. Our aim was to investigate whether a relationship exists between sudden sensorineural hearing loss (SSHL) and a high MPV value. The records of 46 patients who were admitted to the ENT (ear nose throat) ward for SSHL and received medical treatment and 46 patients in a control group were retrospectively screened. The correlation among the levels of the MPV, the number of platelets, and SSHL were evaluated in the two groups. The ages, genders, and the platelet count values of the patients showed a normal distribution in both groups. No significant difference was found for the MPV values between the groups. The MPV is not a predictive parameter in the diagnosis of SSHL.

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“…Of these, it is said that one third recover spontaneously without any treatment [2]. There are different hypotheses regarding the etiology of SSNHL such as infections, vascular catastrophes, autoimmune disease or abnormal cellular stress responses and intracochlear membrane rupture [3]. Because there may be several causes of the symptom SSNHL, the diagnostic test-batteries used are often based on more than one of these hypotheses.…”

Section: Introductionmentioning

confidence: 99%

Assessment of diagnostic approaches to idiopathic sudden sensorineural hearing loss and their influence on treatment and outcome

Nosrati-Zarenoe

¹

,

Hansson

²

,

Hultcrantz

³

2010

Acta Oto-Laryngologica

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Methods:The first 400 patients submitted to the Swedish national database for SSNHL were analyzed. Information was collected at the first visit about the patient's past medical history, potential precipitating events traumata, family medical history, hearing loss, current disease, diagnostic protocol and treatment using questionnaires as well as two audiograms for each patient, one at the first visit to the ENT-clinic and one three months later.Results: 65% of these 400 patients underwent hematological tests and 40% had an MRI/CT.22/160 MRI investigated had pathological findings: five acoustic neuromas, one subdural hematoma, one pons infarction, five vascular abnormalities and ten patients had accidental findings not connected to the hearing tracts. 300 of these 400 patients were evaluated as idiopathic sudden sensorineural hearing loss (ISSNHL); 24% of them had one or more pathological tests. No significant correlation was found between either the MRI findings or the laboratory findings with regard to either treatment or hearing recovery in patients with ISSNHL. Conclusion:Results from a database for SSNHL demonstrate no correlation between laboratory findings, treatment and outcome in 400 patients. The patients with pathological tests were not treated differently from those with normal tests or no tests taken. The value of laboratory findings and MRI might increase if the results are categorized to more specific diagnoses.

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“…Of these, it is said that one third recover spontaneously without any treatment [2]. There are different hypotheses regarding the etiology of SSNHL such as infections, vascular catastrophes, autoimmune disease or abnormal cellular stress responses and intracochlear membrane rupture [3]. Because there may be several causes of the symptom SSNHL, the diagnostic test-batteries used are often based on more than one of these hypotheses.…”

Section: Introductionmentioning

confidence: 99%

Assessment of diagnostic approaches to idiopathic sudden sensorineural hearing loss and their influence on treatment and outcome

Nosrati-Zarenoe¹,

Hansson²,

Hultcrantz³

2009

SOTO

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Methods:The first 400 patients submitted to the Swedish national database for SSNHL were analyzed. Information was collected at the first visit about the patient's past medical history, potential precipitating events traumata, family medical history, hearing loss, current disease, diagnostic protocol and treatment using questionnaires as well as two audiograms for each patient, one at the first visit to the ENT-clinic and one three months later.Results: 65% of these 400 patients underwent hematological tests and 40% had an MRI/CT.22/160 MRI investigated had pathological findings: five acoustic neuromas, one subdural hematoma, one pons infarction, five vascular abnormalities and ten patients had accidental findings not connected to the hearing tracts. 300 of these 400 patients were evaluated as idiopathic sudden sensorineural hearing loss (ISSNHL); 24% of them had one or more pathological tests. No significant correlation was found between either the MRI findings or the laboratory findings with regard to either treatment or hearing recovery in patients with ISSNHL. Conclusion:Results from a database for SSNHL demonstrate no correlation between laboratory findings, treatment and outcome in 400 patients. The patients with pathological tests were not treated differently from those with normal tests or no tests taken. The value of laboratory findings and MRI might increase if the results are categorized to more specific diagnoses.

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Sudden Deafness: Is It Viral?

Cited by 164 publications

References 133 publications

Mean Platelet Volume: Is It a Predictive Parameter in The Diagnosis of Sudden Sensorineural Hearing Loss?

Mean Platelet Volume: Is It a Predictive Parameter in The Diagnosis of Sudden Sensorineural Hearing Loss?

Assessment of diagnostic approaches to idiopathic sudden sensorineural hearing loss and their influence on treatment and outcome

Assessment of diagnostic approaches to idiopathic sudden sensorineural hearing loss and their influence on treatment and outcome

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