Mean Platelet Volume: Is It a Predictive Parameter in The Diagnosis of Sudden Sensorineural Hearing Loss?

Karli, Rıfat; Alaçam, Hasan; Ünal, Recep; Kucuk, Harun; Aksoy, Aziz; Ayhan, Emre

doi:10.1007/s12070-013-0648-4

Cited by 35 publications

(44 citation statements)

References 32 publications

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“…Ulu et al [23] reported significantly higher MPV levels in ISSNHL patients and suggested that increased MPV values indicate the possible causes of ischemia or atherosclerosis in ISSNHL patients. However, Karli et al [24] have reported no significant difference between MPV levels of ISSN-HL patients and controls.…”

Section: Discussionmentioning

confidence: 93%

Evaluation of Procalcitonin and hs-CRP Levels in Sudden Sensorineural Hearing Loss

et al. 2018

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Section: Discussionmentioning

confidence: 93%

Evaluation of Procalcitonin and hs-CRP Levels in Sudden Sensorineural Hearing Loss

et al. 2018

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“…Poorey et al [31] reported an increased level of MPV due to chronic nasal obstruction in patients with deviated nasal septum. Karli et al [6] stated that MPV is not a predictive parameter in the diagnosis of sudden sensorineural hearing loss. Ozbay et al [22] found no significant difference in terms of MPV levels between patients with severe tinnitus and control subjects.…”

Section: Ent Updatesmentioning

confidence: 99%

Assessment of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and mean platelet volume in patients with tinnitus

Bayram¹,

Yaşar²,

Doğan³

et al. 2015

ENT Updates

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Tinnitus is a condition of the ear in which the person perceives sounds without an external source. The estimated prevalence of tinnitus ranges from 5 to 15%, and it becomes more prevalent with older age. [1] Despite the high prevalence of tinnitus, the underlying pathophysiological mechanisms have not been fully clarified. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been defined as novel markers of inflammation and thrombotic events which can be easily measured from the complete blood cell count (CBC). [2] Sudden sensorineural hearing loss, Bell's palsy and vestibular neuritis are certain pathological conditions that have been found to be related to NLR and PLR in otolaryngological practice. [3-5] Mean platelet volume (MPV) is a blood marker related to function and activation of platelets. [6] In the present study, we aimed to investigate the association of NLR, PLR and MPV with tinnitus.

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“…[40][41][42] Mean platelet volume (MPV) is a blood marker related to function and activation of platelets. 43 A study on patients with stroke reported that NLR increase and CRP (C reactive protein) which is an inflammation marker are significantly correlated. 44 The study by Gokhan et al showed NLR scores increase significantly in ischemic and hemorrhagic stroke.…”

Section: Discussionmentioning

confidence: 99%

Study the relationship between nasal polyps, platelet count, mean platelet volume, neutrophil/lymphocyte ratio in patients attending otolaryngology OPD in a tertiary care teaching hospital, West Bengal

Sharma

Raman²,

Ray

et al. 2017

Int J Otorhinolaryngol Head Neck Surg

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Original Research ArticleStudy the relationship between nasal polyps, platelet count, mean platelet volume, neutrophil/lymphocyte ratio in patients attending otolaryngology OPD in a tertiary care teaching hospital, West Bengal ABSTRACTBackground: Nasal obstruction is a common cause of marked nasal septal deviation. It is related strongly with hypoxia. Hypoxic conditions increase mean platelet volume levels. Many studies in literature point out that inflammation related to nasal polyp is mostly dependent on eosinophils and their inflammatory products. Beside eosinophils, platelets may have a role in nasal polyp development. Platelets are involved in hemostasis, tissue repairing and inflammation. Recently, mean platelet volume (MPV) was recognized as a simple inflammatory marker in the inflammatory disease. This study investigated the relationship of nasal polyps with MPV (mean platelet volume), platelet count and NLR (neutrophil to lymphocyte ratio). Methods:The cross-sectional observational study we investigated CBC (complete blood count) parameters of the patients that consulted ENT clinic in a tertiary care teaching hospital, Haldia because of nasal polyp. About 76 patients and 42 controls were included in this study. In all groups, WBC (white blood cell count), RBC (red blood cell count), RDW (red cell distribution width), platelet count, MPV, PDW (platelet distribution width) and NLR parameters from CBC (complete blood count) were compared between patients and controls. Results:Mean WBC values were 6.89±1.33×103/μL in patients with NPs, vs. 7.11±2.32×103/μL in the control group. Mean haemoglobin (Hb) values were 13.19±1.34 g/dL in patients with NPs, vs. 14.1±1.67 g/dl in the control group. Mean MPV values were 9.11 ± 1.08 fL in patients with NPs, vs. 8.32±0.53 fL in the control group. Mean PLT values were 232.38 ± 39.97×103/μL in patients with NPs, vs. 271.44±45.14×103 in the control group. MPV was higher in nasal polyp patients, whereas platelet count was higher in controls. The difference was significant for the mean absolute neutrophil, platelet count, and lymphocyte counts, NLR, PDW and MPV values between the study group and the control group. Conclusions: Platelet count and NLR were significantly lower in patients than the controls, whereas MPV was significantly higher in nasal polyp patients.

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Mean Platelet Volume: Is It a Predictive Parameter in The Diagnosis of Sudden Sensorineural Hearing Loss?

Cited by 35 publications

References 32 publications

Evaluation of Procalcitonin and hs-CRP Levels in Sudden Sensorineural Hearing Loss

Evaluation of Procalcitonin and hs-CRP Levels in Sudden Sensorineural Hearing Loss

Assessment of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and mean platelet volume in patients with tinnitus

Study the relationship between nasal polyps, platelet count, mean platelet volume, neutrophil/lymphocyte ratio in patients attending otolaryngology OPD in a tertiary care teaching hospital, West Bengal

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