Sudden Cardiac Death in Patients With Hypertrophic Cardiomyopathy

Ватутин, Н. Т.; Тарадин, Г. Г.; Maron, Martin S.; Шевелек, А. Н.

doi:10.18565/cardio.2016.1.56-65

Kardiologiia

2016

DOI: 10.18565/cardio.2016.1.56-65

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Sudden Cardiac Death in Patients With Hypertrophic Cardiomyopathy

Н. Т. Ватутин¹,

Г. Г. Тарадин²,

Martin S. Maron³

et al.

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Cited by 5 publications

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“…Currently, HCM is considered as the major cause of sudden cardiac death in young people, since it can be the first and the last manifestation of the disease [10]. Based on the data from autopsies of young people, conducted by various researchers in different years, N. Т. Vatutin et al in their work showed that the incidence of HCM as a cause of sudden death varied from 7 % to 25 % [11]. Clinical manifestation of HCM can be revealed at any age, but more frequently in the 3 rd and 4 th decades of life, and rarely first symptoms appear after 60 years of age [12].…”

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Myocardial morphology in hypertrophic cardiomyopathy: the current state of the problem

Balabai

2019

ZMJ

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Цель работы -на основании данных современных источников научной литературы проанализировать морфологические особенности миокарда при гипертрофической кардиомиопатии.Обзор освещает современные взгляды на особенности структурного ремоделирования миокарда левого желудочка сердца у больных гипертрофической кардиомиопатией, приведены наиболее распространенные классификации данной патологии. Уделено внимание проблеме взаимосвязи фигур дизарея кардиомиоцитов и фиброза миокарда. Важное патогенетическое звено развития сердечной недостаточности, усиливающее связь между нарушениями гистоархитектоники миокарда и прогрессирующей ишемией сердца при гипертрофической кардиомиопатии -«болезнь малых сосудов».Выводы. Несмотря на большое количество исследований гипертрофической кардиомиопатии, в научной литературе нет единого мнения об этиологии и патогенезе гипертрофической кардиомиопатии. Противоречивые сведения о наличии взаимосвязи и последовательности развития фигур дизарея, гипертрофии кардиомиоцитов, интерстициального фиброза, изменений микроциркуляторного русла и митрального клапана при гипертрофической кардиомиопатии затрудняют поиски адекватного этиотропного лечения. Полиморфизм клинических и морфологических проявлений гипертрофической кардио миопатии требует от кардиологов и патогистологов совместных усилий по изучению данной болезни.A -research concept and design; B -collection and/or assembly of data; C -data analysis and interpretation; D -writing the article; E -critical revision of the article; F -final approval of the article The objective. Based on the modern sources of scientific data to analyze the morphological features of the myocardium in hypertrophic cardiomyopathy.The paper presents a literature review on current views on the features of structural remodeling of the left ventricular myocardium in patients with hypertrophic cardiomyopathy, as well as the most common classifications of this pathology. The emphasis is made on the problem of the interrelation of myocardial disarray and fibrosis.The "small vessel disease" is an important pathogenetic link in the development of heart failure, which enhances the relation between disorder of myocardial histoarchitectonics and progressive cardiac ischemia in hypertrophic cardiomyopathy. Conclusions.Notwithstanding the numerous research data on hypertrophic cardiomyopathy, no consensus among the authors regarding the etiology and pathogenesis of hypertrophic cardiomyopathy exists to date. Controversial data on the interrelation and sequence of disarray, myocardial hypertrophy, interstitial fibrosis, changes in the microvasculature and structural changes of the mitral valve in patients with hypertrophic cardiomyopathy hamper the search for adequate etiotropic treatment.Polymorphism of clinical and morphological manifestations of hypertrophic cardiomyopathy requires collaborative efforts to study the disease by cardiologists and pathologists.Морфологія міокарда при гіпертрофічній кардіоміопатії: сучасний стан проблеми А. А. Балабай Мета роботи -на підставі даних сучасни...

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Myocardial morphology in hypertrophic cardiomyopathy: the current state of the problem

Balabai

2019

ZMJ

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Surgical myectomy in patients with obstructive hypertrophic cardiomyopathy and concomitant cardiac diseases

Taradin,

Solovyov,

Ignatenko

et al. 2023

Kardiol. serdechno-sosud. khir.

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Atrial Fibrillation in Hypertrophic Cardiomyopathy

Игнатенко

Тарадин

Ватутин

et al. 2021

Arhivʺ vnutrennej mediciny

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The current information about features of atrial fibrillation in patients with hypertrophic cardiomyopathy is presented in this review. The data about prevalence, pathogenesis and its various complications in these patients are disclosed. The article contains updated clinical recommendations of authoritative medical societies on the discussing problem. There is detailed discussion of risk factors of atrial fibrillation onset in setting of hypertrophic cardiomyopathy with demonstration of results of different studies concerning to investigation of relationship between risk factors and probability of the arrhythmia development. There is description of detection methods, clinical manifestations, and the course of atrial fibrillation in patients with hypertrophic cardiomyopathy. The contemporary literature data are presented regarding to the management of patients with atrial fibrillation with use of anticoagulants, antiarrhythmic drugs, indications for performing of radiofrequency ablation and results of studies concerning long-term efficacy of such procedure are demonstrated. The discussion on the management of the patients in cases of sinus rhythm restoration or maintenance failure is described.

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Sudden Cardiac Death in Patients With Hypertrophic Cardiomyopathy

Cited by 5 publications

References 0 publications

Myocardial morphology in hypertrophic cardiomyopathy: the current state of the problem

Myocardial morphology in hypertrophic cardiomyopathy: the current state of the problem

Surgical myectomy in patients with obstructive hypertrophic cardiomyopathy and concomitant cardiac diseases

Atrial Fibrillation in Hypertrophic Cardiomyopathy

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