Successful yolk-sac tumor treatment with fertility-sparing partial oophorectomy

Abstract

Yolk-sac tumors account for about 20% of ovarian germ cell tumors and occur predominantly in women below 35 years of age. Modern evidence-based treatment strategies have ensured long term post-treatment survival, but with increased survival, attention has been turned to an urgent need for developing fertility sparing treatment strategies. In this report we describe the successful treatment of a young woman who was able to conceive and deliver two children, in spite of the loss of one ovary two years prior to being diagnosed with an ovarian yolk-sac tumor on the remaining ovary.

Yolk sac tumor, a rare and challenging ovarian malignancy: case report

“…Surgery should be by an open procedure to ensure complete removal of the affected ovary with its intact tumor capsule rather than broken or ruptured. 2,3 Operative details, histopathological findings, tumor markers and imaging studies are important for correct staging and management planning. With the advent of chemotherapy BEP, the prognosis has remarkably increased from 14% to more than 95% in advance cases of MOGCTs.…”