Successful Treatment of Mucosa-Associated Lymphoid Tissue Lymphoma of the Rectum with Radiation Therapy: Report of a Case

Foo, Marcus; Chao, Michael; Gibbs, Peter; Guiney, Michael; Jacobs, Rodney

doi:10.1007/s10350-008-9379-0

Cited by 16 publications

(9 citation statements)

References 29 publications

(15 reference statements)

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“…In a review of 34 cases of rectal MALT lymphoma none had underlying ulcerative colitis. 9 None of the patients was less than 30 years of age. The lesions were polypoid and were diagnosed by endoscopic biopsy unlike our patient where the presence of MALT lymphoma was masked by the presence of ulcerations and pseudopolyps due to ulcerative colitis.…”

Section: Discussionmentioning

confidence: 97%

“…About one-third to onehalf of reported colorectal lymphomas are MALT type, commonly affecting the cecum, with rectum being an unusual site. 8,9 Rarely, large T-cell, 10 mixed B cell and T cell 11 and NK/Tcell 12 lymphoma have also been reported. In a review of 34 cases of rectal MALT lymphoma none had underlying ulcerative colitis.…”

Section: Discussionmentioning

confidence: 99%

“…15 Even though MALT lymphoma is believed to have an indolent course, majority of cases of rectal MALT lymphoma reported so far have been treated with surgery, chemotherapy or a combination of both. 9 Spontaneous regression of rectal MALT lymphoma after antibiotic treatment has been noted in the presence as well as absence of Helicobacter pylori infection in patients without underlying inflammatory bowel disease. Local endoscopic therapy with or without treatment for H. pylori has been proposed to be a reasonable treatment by some authors.…”

Section: Discussionmentioning

confidence: 99%

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Rectal MALT lymphoma associated with ulcerative colitis

Mangla¹,

Pal²,

Dash³

2012

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Rectal MALT lymphoma associated with ulcerative colitis

Mangla¹,

Pal²,

Dash³

2012

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“…Only 4 published cases of primary rectal MALT lymphoma treated with radiotherapy were found [9, 10, 14, 15], which are summarized along with our patients in table 1 . Patient age ranged from 26 to 65 years (mean 53.8 years).…”

Section: Discussionmentioning

confidence: 99%

Helicobacter pylori-Negative Primary Rectal MALT Lymphoma: Complete Remission after Radiotherapy

Okamura

Suga

Iwaya

et al. 2012

Case Rep Gastroenterol

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Rectal mucosa-associated lymphoid tissue (MALT) lymphoma is a rare condition. Although the majority of patients undergo surgical resection, a definitive treatment for rectal MALT lymphoma has not yet been established. In the present study, we report the outcome of radiotherapy in 3 patients with rectal MALT lymphoma. Our cohort ranged from 56 to 65 years of age. The male/female ratio was 1:2, and all patients were in stage I (Lugano classification) of the disease. Endoscopic findings revealed elevated lesions resembling submucosal tumors in 2 patients, and a sessile elevated lesion with a nodular surface in 1 patient. One of the 3 patients underwent magnifying endoscopy with crystal violet staining that demonstrated a type I pit pattern (Kudo’s classification) lesion with a broad intervening area caused by the upthrust of the tumor from the submucosa. All patients tolerated radiotherapy at doses of 30 Gy without major complications and achieved complete remission. Follow-up ranged from 13 to 75 months (mean 51.0 months), revealing no recurrence of MALT lymphoma. As such, we propose radiotherapy to be a safe and effective means for treating rectal MALT lymphoma.

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“…Its development is thought to be closely associated with H. pylori infection. Rectum is an uncommon site for MALT lymphomas to develop, comprimising less than one percent of all colorectal malignancies [2]. …”

Section: Introductionmentioning

confidence: 99%

MALT lymphoma of the rectum, presenting with rectal prolapsus: a case report

Ersöz¹,

Toros²,

Bektaş³

et al. 2010

Cases Journal

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Up to now, there have been only a few reported cases of Mucosa-associated lymphoid tissue (MALT) lymphomas arising in the rectum. Its clinical presentation is indistinguishable from that of rectal carcinoma but the treatment is apparently different. Symptoms of primary lymphomas involving the rectum include; anorexia, weight loss, change in bowel habits, obstruction, and bleeding. These symptoms are not disease specific and can be seen in many other gastrointestinal disorders. Patients with polypoid masses may present with obstruction symptoms. In this rare case, a female patient admitted to the emergency service with prolapsus of a rectal mass.The optimal treatment of rectal MALT lymphoma is not well defined yet, given the rarity of the disease. Surgical resection of the localized lesion and following adjuvant chemotherapy has proved to be an effective treatment option. However, a close and long-lasting follow-up is important.

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Successful Treatment of Mucosa-Associated Lymphoid Tissue Lymphoma of the Rectum with Radiation Therapy: Report of a Case

Cited by 16 publications

References 29 publications

Rectal MALT lymphoma associated with ulcerative colitis

Rectal MALT lymphoma associated with ulcerative colitis

Helicobacter pylori-Negative Primary Rectal MALT Lymphoma: Complete Remission after Radiotherapy

MALT lymphoma of the rectum, presenting with rectal prolapsus: a case report

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