Successful treatment of cytomegalovirus encephalitis in a patient with Hodgkin's disease in remission

Abstract

Cytomegalovirus encephalitis is a rare but life-threatening infection in non-AIDS patients. To our knowledge, no case that followed conventional treatment for Hodgkin's lymphoma has been reported. We present a patient with Hodgkin's disease in complete remission after combined modality treatment who was succesfully treated with a combination of ganciclovir and foscarnet.

Fatal outcome in two girls with Hodgkin disease complicating ataxia-telangiectasia (Louis-Bar syndrome) despite favorable response to modified-dose chemotherapy

“…According to the HD study center in Germany, this is the first HD patient ever to die from CMV infection. Van Droogenbroeck et al [8] have described a CMV infection of the central nervous system in an HD patient in remission as a rare complication following conventional polychemotherapy. The risk of developing CMV infections is much higher if an additional immunodeficiency exists.…”

Disseminated infection of the digestive tract caused by cytomegalic virus in a patient with Hodgkin's disease

“…CMV infection with clinically expression was described in normal subjects, but is far more frequent in immunosuppressed patients -AIDS, graft organs and, rarely, Hodgkin's disease. In the literature there are a few cases of CMV infection with clinical expression in Hodgkin's disease, with specific gastritis [1], cutaneous [2], retinitis [3], encephalitis [4,5].…”