Successful treatment of a patient with obesity, type 2 diabetes and hypertension with the paleolithic ketogenic diet

Abstract

International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties.Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations. IJCRI publishes SUMMARYMetabolic syndrome is made up of a cluster of conditions including obesity, impaired insulin sensitivity, hypertension and altered lipid profile. These conditions are also considered as risk factors for type 2 diabetes and cardiovascular disease. Occurrence of these conditions is on the rise worldwide despite of the increasing number of drugs used. There is evidence from the literature indicating that intervention with low carbohydrate diets, including the paleolithic diet, may be beneficial in the metabolic syndrome. Except for one study with the paleolithic diet these investigations are short in duration. Another limitation is that they do not give clues how to deal with medications patients are treated with. Third, in these studies the paleolithic diet did not produce ketosis which may limit the clinical effectiveness. Here we present a case of a patient with metabolic syndrome and excessively medicated. The patient shifted toward the paleolithic ketogenic diet and was able to discontinue medication, lost weight and her glucose parameters markedly improved. Her hypertension normalized. Currently she is on the diet for 22 months and show good adherence as also confirmed by laboratory tests. She is free of symptoms and no side-effects emerged. Previously we reported cases with epilepsy and type 1 diabetes successfully treated with the same diet. We suggest that a dietary intervention with the paleolithic ketogenic diet may be a simple, feasible and cost-effective method in some forms of chronic disorders in highly motivated patients.(This page in not part of the published article.)

A child with type 1 diabetes mellitus (T1DM) successfully treated with the Paleolithic ketogenic diet: A 19-month insulin-freedom

“…The child's asthma, eczema, epistaxis, bloated abdomen, frequent upper respiratory infections and fatigue disappeared. Positive effects are in line with those presented in our other patients put on the Paleolithic ketogenic diet [13][14][15][16]. Although we did not use vitamin or other supplements no deficiencies emerged.…”

Treatment of Rectal Cancer with the Paleolithic Ketogenic Diet: A 24-months Follow-up

“…It is known that plant oils, grains and dairy, among their other possible negative effects, may promote inflammation [17]. On the contrary, the paleolithic ketogenic diet, which is based on animal fat, meat and offal, seems to have an anti-inflammatory effect, as also seen in our other patients on the same diet [18][19][20][21][22][23][24][25]. In addition, while the classical ketogenic diet is known to induce nutrient deficiencies [29], the paleolithic ketogenic diet seems to supply optimal amounts of micronutrients as shown by the absence of deficiency symptoms and the normalization of laboratory parameters including iron, magnesium and vitamin levels, and normal function of the liver, kidney and thyroid gland.…”

“…An increasing number of studies, as also reviewed by a recent metaanalysis [15], indicate metabolic benefits of the human evolutionary diet also known as the stone age diet [16] or paleolithic diet [17]. In recent years we have published a series of case studies where type 1 diabetes [18,19], type 2 diabetes [20], epilepsy [21,22], Gilbert's syndrome [23] and Crohn's disease [24] where was successfully treated by the paleolithic ketogenic diet, an animal fat-meat based diet. In our most recent case study we reported on halted progression of soft palate cancer for 20 months in a patient on the paleolithic ketogenic diet [25].…”

Complete Cessation of Recurrent Cervical Intraepithelial Neoplasia (CIN) by the Paleolithic Ketogenic Diet: A Case Report

“…Previously we have published a case of soft palate cancer halted by the paleolithic ketogenic diet for 20 months [10]. We also reported successful management of cases of autoimmune conditions including type 1 diabetes [24,25] and cases with epilepsy [26,27] and metabolic syndrome [28] using the paleolithic ketogenic diet. In another case study we reported that a full dietary adherence is needed to halt disease progression in rectal cancer [29].…”