Complete Cessation of Recurrent Cervical Intraepithelial Neoplasia (CIN) by the Paleolithic Ketogenic Diet: A Case Report

Abstract

Background: Ketogenic diets have repeatedly been suggested for the treatment of cancer. To date, only a few case studies reporting long term benefits associated with such diets have been published. Case report: Here we present a case where recurrent cervical intraepithelial neoplasia (CIN), a premalignant condition of cervical cancer, was successfully treated with the paleolithic ketogenic diet. The patient had a history of high grade CIN in 2011, which was successfully treated with cervical conization and fractional curettage. In October 2015 she was found to have a recurrence of high grade CIN (HSIL: High Grade Squamous Intraepithelial Lesion). The patient was then commenced on the paleolithic ketogenic diet and her repeat Pap (Papanicolaou) smear three months later was found to have reverted to normal. The patient has remained on the paleolithic ketogenic diet for 26 months, her repeat smears have stayed normal, and she is free of symptoms and side effects. Conclusion: We conclude that the diet was effective and safe in this patient. As a major benefit the patient was able to avoid a hysterectomy, which is the standard treatment for recurrent high-grade CIN. We believe that the paleolithic ketogenic diet combines benefits of both paleolithic and classical ketogenic diets, while excluding their disadvantages.

Impact of Different Types of Diet on Gut Microbiota Profiles and Cancer Prevention and Treatment

“…The association with high microbiome diversity and their putatively anti-inflammatory properties would make PDs interesting to investigate in future clinical studies as adjuncts to cancer therapy. Recently, a Hungarian group published several case reports of a ketogenic version of a PD appearing therapeutic against tumor growth [71,72,73], demonstrating the potential of this approach.…”

4-Year Long Progression-Free and Symptom-Free Survival of a Patient with Recurrent Glioblastoma Multiforme: A Case Report of the Paleolithic Ketogenic Diet (PKD) Used as a Stand-Alone Treatment After Failed Standard Oncotherapy

“…We put forward that normalizing intestinal permeability is key to controlling inflammation through the application of PKD. Accordingly, we generally see a decrease in the inflammatory markers after a shift toward the PKD (Tóth et al, 2018 and the referenced case studies with the PKD). In our glioblastoma patient, intestinal permeability, as measured by the PEG400 challenge test, also indicated normal intestinal permeability while on the PKD.…”

38-Month Long Progression-Free and Symptom-Free Survival of a Patient With Recurrent Glioblastoma Multiforme: A Case Report of the Paleolithic Ketogenic Diet (PKD) Used As a Stand-Alone Treatment after Failed Standard Oncotherapy

“…Previously, we have published three cancer case reports, where the PKD resulted in regression or stable disease. In a patient with recurrent cervical intraepithelial neoplasia, the PKD resulted in complete reversal (Tóth et al, 2018). In another patient with an aggressive soft palate cancer, the PKD resulted in progression-free status .…”

“…Thus far, we have published several case reports of patients who have been successfully treated with the PKD. These include: type 2 (Tóth and Clemens, 2015a) and type 1 diabetes (Tóth and Clemens, 2014;2015b); Crohn's disease ; Gilbert's syndrome (Tóth and Clemens, 2015c); epilepsy (Clemens et al, 2013(Clemens et al, , 2015; complete reversal of cervical intraepithelial neoplasia (Tóth et al, 2018); halted progression of soft palate cancer and regression of rectal cancer ( Here we present a case report of a patient with glioblastoma multiforme. Initially, the patient had been treated with standard oncotherapy including surgery, radiotherapy and chemotherapy.…”