Successful Spontaneous Pregnancy after Treatment for Ewing Sarcoma including Sacrectomy

Hockertz, Thomas; Veličković, Momčilo

doi:10.1155/2018/2484036

Cited by 3 publications

(4 citation statements)

References 21 publications

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“…4 We found that the caesarean birth rate was higher compared with other series. 10 38 39 Among women seeking elective cesarean birth, reasons included perceived physical joint limitations in hips, pelvis, and abdomen. 4…”

Section: Discussionmentioning

confidence: 99%

Maternal and Fetal Outcomes in Pregnancies affected by Bone and Soft Tissue Tumors

Figueiró-Filho

Al-Sum

Parrish

et al. 2018

AJP Rep

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Objective This study was aimed to describe perinatal outcome of a cohort of pregnant patients with bone and soft tissue tumors and to compare the current series with our group's previously reported experience. Methods Pregnant women diagnosed before and during pregnancy were identified, retrospectively, for the years 2004 to 2014. Relevant maternal and neonatal data were collected. Results Forty-eight patients were identified. Ten cases were diagnosed during pregnancy. Pelvis, abdomen, and extremities were the most common tumor locations. Osteosarcoma, liposarcoma, and Ewing's sarcoma were the most common histological types and comprise more than 50% of the cases. Metastases occurred in nine cases. Most of the cases (60%) were treated surgically during pregnancy and delivery occurred at term. Chemotherapy was delayed until after delivery. There were no perinatal or infant deaths. Patients presented with advanced maternal disease in 18% in previous report (1983–2003) versus 40% in present report (2004–2014). Metastases were present in 40% and maternal death rate was approximately 20% in both cohorts. Conclusion Pregnant women with bone and soft tissue tumors are candidates for standard surgical management during pregnancy. Other treatments, such as chemotherapy and radiotherapy must be evaluated for each woman on a case-by-case basis. Iatrogenic prematurity was common in our findings.

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Section: Discussionmentioning

confidence: 99%

Maternal and Fetal Outcomes in Pregnancies affected by Bone and Soft Tissue Tumors

Figueiró-Filho

Al-Sum

Parrish

et al. 2018

AJP Rep

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“…31 The safety of chemotherapy during pregnancy is based upon a few case series and not all multiagent regimens have been studied in detail. 32 33 A 10-year retrospective study in Belgium focusing in pregnant women with cancer, prenatally exposed to cytotoxic treatment, demonstrated that more than 50% of neonates were admitted to the neonatal intensive care unit due to preterm labor. 9…”

Section: Discussionmentioning

confidence: 99%

Obstetrical Outcomes of Head and Neck (Nonthyroid) Cancers: A 27-Year Retrospective Series and Literature Review

Figueiró-Filho

Horgan

Muhanna

et al. 2019

AJP Rep

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Objective To describe the clinical presentation and obstetrical outcomes of nonthyroid head and neck cancers (HNCs), and to review literature on this rare condition in pregnancy. Study Design Pregnant women with nonthyroid HNC were identified retrospectively from 1990 to 2017. Maternal, neonatal, pregnancy, and demographic data were collected. A review of the literature from January 1980 to May 2018 was performed. Results Over the 27-year time period, 16 women with history of nonthyroid HNC were identified (9 diagnosed during and 7 diagnosed before current pregnancy). The cases were analyzed in detail and the most updated review of management of each type of HNC was provided. Conclusions HNCs are rare with diagnosis and management challenges during pregnancy. In this series, the cases diagnosed and managed previously to pregnancy presented better perinatal outcomes than the cases presented during pregnancy. The maternal outcomes appeared similar for HNC diagnosed before or after pregnancy.

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“…Метастазы в тканях головы и шеи встречаются в 12,5%, а в центральной нервной системе -в 10-37% случаев [11]. Инвазивный рост опухоли в окружающие мягкие ткани [23] вовлекает в патологический процесс регионарные лимфатические узлы (поражаются в 5-15% случаев) [2]. До применения системной терапии метастазы развивались почти у 90% больных [8].…”

Section: метастазированиеunclassified

“…Успешное применение хирургического лечения и послеоперационной лучевой терапии в сочетании с хи миотерапией значительно повысило выживаемость больных с саркомой Юинга. Так, в 1960-х годах примерно половина пациентов умирала в течение первого года с момента установления диагноза, двухлетняя выживаемость составляла всего 21% [23,44]. В настоящее время общая пятилетняя выживаемость составляет 53-75% [22,42,45], хотя имеются сообщения о 5-и 10-летней выживаемости на уровне 84 и 74% соответственно [12,27].…”

Section: лечениеunclassified

Sechenov First Moscow State Medical University (Sechenov University)

Самбурова

Жевак

Литвицкий

2019

Vopr. sovr. pediatr.

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Successful Spontaneous Pregnancy after Treatment for Ewing Sarcoma including Sacrectomy

Abstract: Ewing sarcomas are highly malignant bone tumors and usually occur in childhood. Radiation therapy, chemotherapy, and surgical methods increase the survival rate of the affected patient, but infertility and reduced reproductive capacity are common late effects of pediatric cancer treatment.

Cited by 3 publications

References 21 publications

Maternal and Fetal Outcomes in Pregnancies affected by Bone and Soft Tissue Tumors

Maternal and Fetal Outcomes in Pregnancies affected by Bone and Soft Tissue Tumors

Obstetrical Outcomes of Head and Neck (Nonthyroid) Cancers: A 27-Year Retrospective Series and Literature Review

Sechenov First Moscow State Medical University (Sechenov University)

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