Successful repair of myocardial free wall rupture after thrombolytic therapy for acute infarction

Park, Woosup M.; Connery, Cliff P.; Hochman, Judith S.; Tilson, M. David; Anagnostopoulos, Constantine E.

doi:10.1016/s0003-4975(00)01928-7

Cited by 17 publications

(15 citation statements)

References 26 publications

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“…The usual approach is pericardial patch closure of the defect or, less frequently, infarctectomy with patch placement and ventricular wall reconstruction [12][13][14]. Pericardiocentesis should be done only as an emergency desperate measure if cardiac tamponade occurs while a surgical repair is planned [15,16].…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Fatal Left Ventricular Free Wall Rupture: Case Report and Short Review

Abdelnaby¹,

Saleh²,

Haleem³

et al. 2017

J Cardiovasc Dis Diagn

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Left ventricular free wall rupture (LVFWR) is a rare, yet lethal, complication of acute myocardial infarction (AMI), occurring in approximately 2% of cases. In the era of percutaneous coronary intervention, however, it is less frequently encountered.We were confronted with a case of AMI complicated with LVFWR after receiving thrombolytic therapy. The diagnosis was established using transthoracic echocardiography (TTE). Unfortunately, the patient passed away before surgical intervention. This case demonstrates the importance of prompt diagnosis and management of such a lethal complication.

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Section: Discussionmentioning

confidence: 99%

A Rare Case of Fatal Left Ventricular Free Wall Rupture: Case Report and Short Review

Abdelnaby¹,

Saleh²,

Haleem³

et al. 2017

J Cardiovasc Dis Diagn

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“…After this period, the impact of thrombolytic therapy remains uncertain. The LATE (Late Assessment of Thrombolytic Efficacy) Study was not able to conclusively demonstrate that late use of thrombolysis increases the rupture rate, despite the fact that rupture occurs earlier [2,4]. The reperfusion phenomenon seems to favor early heart rupture due to the transformation of the ischemic infarction into hemorrhagic infarction [4].…”

Section: Commentsmentioning

confidence: 98%

“…This occurs, generally, at the weakest site of the ventricular wall, located in the non-complacent zone of the infarcted area. The use of thrombolytic therapy in the treatment of AMI has an important impact in reducing the overall mortality, but the rupture rate remains unaltered [4].…”

Section: Commentsmentioning

confidence: 99%

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Reparo de rotura de ventrículo esquerdo após uso de tenecteplase no tratamento do infarto agudo do miocárdio

Guedes¹,

Filho²,

Hueb³

et al. 2005

Rev Bras Cir Cardiovasc

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Reparo de rotura de ventrículo esquerdo após uso de tenecteplase no tratamento do infarto agudo do miocárdioSurgical repair of left ventricular rupture after the use of tenecteplase in the treatment of acute myocardium infarction AbstractThe use of thrombolytic agents in the treatment of acute myocardium infarction represented an important impact in the reduction of overall mortality. But this did not alter the cardiac rupture rate. This complication must be recognized and treated quickly. The authors report on a case of surgical repair of an early left ventricle rupture, after the use of tenecteplase in association with non-fractioned heparin for the treatment of acute myocardium infarction.Descriptors: Myocardial infarction. Thrombolytic therapy, adverse effects. Heart rupture, post infarction.Article received in February, 2005 Article accepted in April, 2005Resumo A utilização do trombolítico no tratamento do infarto agudo do miocárdio apresentou um impacto importante na diminuição da mortalidade geral, porém não alterou a incidência da rotura cardíaca. Esta complicação deve ser reconhecida e tratada rapidamente, necessitando um alto nível de suspeição clínica. Os autores relatam um caso de reparo cirúrgico de rotura precoce de ventrículo esquerdo, após utilização de tenecteplase associado à heparina não fracionada, no tratamento do infarto agudo do miocárdio.Descritores: Infarto do miocárdio. Terapia trombolítica, efeitos adversos. Ruptura cardíaca pós-infarto. 183GUEDES, MAV ET AL -Surgical repair of left ventricular rupture after the use of tenecteplase in the treatment of acute myocardium infarction Braz J Cardiovasc Surg 2005; 20(2): 182-185

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“…In the rare occasions when the diagnosis is made and the patient is resuscitated, an immediate transfer to the operating theater should be made in order to attempt a life saving surgical repair. Principles of repair of left ventricular free wall rupture are to stop the bleeding, anchor the repair on healthy tissue, and minimize distortion of heart geometry [17,18]. The surgical technique in such cases has been moved from large patches and running suture techniques towards a more or less sutureless approach utilizing large patches and bio-glue.…”

Section: Free Wall Rupturementioning

confidence: 99%

Acute heart failure: is there a role for surgery?

Pitsis¹,

Anagnostopoulos

2007

Heart Fail Rev

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Many of the disorders and lesions leading to acute heart failure can be treated surgically. Modern surgical techniques like the off pump coronary surgery, newer techniques for the surgical treatment of the mechanical complications of acute MI and valvular reparative techniques have been added to the surgical armamentarium in recent years. Modern ventricular assist devices have started their career in the clinical arena promising to be less invasive. At the same time the spectrum of indications for mechanical circulatory support continues to witness a rapid expansion. Technical advances have led to an evolution of surgical strategies. Heart failure surgery is now in a position to offer improved outcomes, avoidance of recurrence of acute heart failure or the development of advanced chronic heart failure.

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Successful repair of myocardial free wall rupture after thrombolytic therapy for acute infarction

Cited by 17 publications

References 26 publications

A Rare Case of Fatal Left Ventricular Free Wall Rupture: Case Report and Short Review

A Rare Case of Fatal Left Ventricular Free Wall Rupture: Case Report and Short Review

Reparo de rotura de ventrículo esquerdo após uso de tenecteplase no tratamento do infarto agudo do miocárdio

Acute heart failure: is there a role for surgery?

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