Successful photodynamic therapy in a pediatric patient with difficult warts

Abstract

Many clinical studies reported the safety and efficacy of PDT in the treatment of VWs. Chong and Kang reported complete healing of a recalcitrant acral VW after three PDT sessions. 5 Recently, Huang et al. reported that, compared with cryotherapy, the combination of superficial shaving and PDT results in a better healing and a lower recurrence rate of warts. 4 In our case, clearance of warts was achieved after only two sessions, with minimal side effects and no recurrence at one-year follow-up. In conclusion, PDT may represent a relatively new therapeutic modality for some patients with warts, especially where other treatments have shown no or minimal improvement, or in whom invasive therapies should be avoided or not well tolerated.

Photodynamic therapy in pediatric age: Current applications and future trends

“…In each session, the patient experienced mild burning sensation. Complete clearance of the treated warts was seen 6 weeks after the second treatment with no recurrences at 1-year follow-up (Borgia et al, 2020b). Huang et al described the exciting case of an 18-year-old female who completely resolved her 2 year history of resistant multiple warts in the right foot after curettage plus PDT.…”

“…Overall 12 pediatric patients with cutaneous viral warts were treated with various concentrations of ALA, achieving complete response in almost all cases ( Borgia et al, 2020b ; Huang et al, 2019 ; Wu et al, 2019 ).…”

Photodynamic therapy for pediatric genital warts: A case report

“…6 In this study, we confirm the high efficacy and safety of C-PDT with 5-ALA in the pediatric setting. 4,7,8 An otherwise healthy 5-year-old female was brought to our attention by her parents for a 30-months history of multiple skin-colored, verrucous papules in the perineal area (Figure 1A). She had been previously visited by many physicians (both pediatricians and dermatologists) with a diagnosis of GWs, and treated with imiquimod 5% cream and cryotherapy, which were ineffective, and poor tolerated by the patient.…”