Successful ICSI in an azoospermic and kidney transplant man with type 1 primary hyperoxaluria and first histopathological testicular findings described in the literature

Balmori, Carlos; Guillén, Alfredo; Montans, J.; Bronet, F.; García-Velasco, Juan A.

doi:10.1111/and.12230

Cited by 4 publications

(2 citation statements)

References 12 publications

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“…The second report described 8 couples who pursued ICSI with resulting successful pregnancies in 4 couples and live births in 3 (48). In addition to these early reports, successful ICSI has been reported in a variety of unique male transplant recipient patient populations including cystinosis (49), hyperoxaluria with cryptorchidism (50), and oligospermic renal transplant male recipient with female liver transplant recipient (51). Taken together, this body of literature suggests that ART is a viable option for couples with male infertility following renal transplant, albeit with mixed success.…”

Section: Assisted Reproductionmentioning

confidence: 99%

Male infertility in renal failure and transplantation

Lundy¹,

Vij²

2019

Transl. Androl. Urol

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The global disease burden of end stage renal disease (ESRD) is growing rapidly, and organ transplantation remains the gold standard for improving both the quality and quantity of life particularly in young adults. It is therefore critical to understand the effect of ESRD and renal transplantation on male fertility. Many men in renal failure exhibit subfertility or infertility due to several factors including hypogonadism, erectile dysfunction (ED), and direct impairment of spermatogenesis with spermatotoxicity and late stage maturational arrest causing oligospermia or azoospermia. Kidney transplantation has been shown to rescue some-but not all-of these defects, with normalization of reproductive hormonal parameters, improvement in semen parameters (sperm count, motility, morphology), and partial restoration of erectile function. This improvement in fertility is sufficient for a subset to father children either naturally or with assisted reproduction. In this review, we summarize the literature regarding fertility in men with chronic kidney disease (CKD) and on dialysis, and we describe the changes associated with renal transplantation.

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Section: Assisted Reproductionmentioning

confidence: 99%

Male infertility in renal failure and transplantation

Lundy¹,

Vij²

2019

Transl. Androl. Urol

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“…No peculiar contraindications to TeSE are reported in RT recipients. Recently, the first case of a successful intracistoplasmatic injection of spermatozoa (ICSI) in an azoospermic and RT man has been described (99).…”

Section: Evidence Synthesismentioning

confidence: 99%

Urological Consequences following Renal Transplantation: A Review of the Literature

et al. 2015

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Renal transplant (RT) represents the treatment of choice for end-stage renal disease (ESRD) but harbours a wide range of possible complications and therapeutic challenges of urological competence. Dialysis years and clinical medical background of these patients are risk factors for sexual dysfunction and lower urinary tract symptoms (LUTS). On the contrary, RT itself may have a number of possible surgical complications such as ureteral stenosis and urinary leakage, while immunosuppressive treatment is a known risk factor for de-novo malignancies.The present review describes the main urologic problems of RT patients and their up-to-date treatment options according to the most recently available literature evidences.

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