Nonneoplastic Diseases of the Testis

Nistal, Manuel; Paniagua, Ricardo; González‐Peramato, Pilar

doi:10.1016/b978-0-323-54941-7.00012-8

Cited by 4 publications

(6 citation statements)

References 2,985 publications

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“…Orchiectomy, testicular parenchyma-preserving enucleation of the cyst, and conservative surveillance using ultrasonography are the three options available to patients and doctors. Ultrasound studies have indicated that the SC of the testis has little potential for growth [2]. More and more doctors are advocating a "watch and wait" strategy in recent years.…”

Section: Discussionmentioning

confidence: 99%

“…The SC has no spermatozoa and ranges from 2 to 18 mm in diameter [2]. In the present study, we elucidated the pathological features of an SC in the right testis of an elderly Japanese man with prostatic acinar adenocarcinoma of the bilateral lobes.…”

mentioning

confidence: 88%

“…Testicular simple cysts (SCs) are infrequent benign cystic lesions that contain clear serous fluid within the testicular parenchyma [1]. These cysts exhibit a bimodal distribution in adults and infants, with peaks at eight months and 60 years of age [2]. The lining of the testicular SC typically consists of a flat to cuboidal epithelium, specifically mesothelial cells [3].…”

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confidence: 99%

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A Simple Cyst of the Testis was Found Incidentally during Castration for Prostatic Cancer

Tachibana,

Hamayasu,

Nakagawa

et al. 2023

Preprint

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Simple cysts (SCs) within the testes are rare in adults. The testicular SC lining comprises mesothelial cells. This report presents a case involving the accidental discovery of a castration-worthy SC in the right testis of a Japanese man in his 90s who was diagnosed with prostatic adenocarcinoma. Microscopic analysis revealed that the cystic wall was covered with flat to cuboidal mesothelial cells. Immunohistochemistry demonstrated mesothelial cell positivity for calretinin, Wilms tumor 1 (WT-1), Hector Battifora mesothelial epitope-1 (HBME-1), and cyclin-dependent kinase inhibitor p16 (p16INK4a). Notably, no human papillomavirus (HPV) in situ hybridization was detected. This report outlines an exceptionally rare instance of a simple cyst within the testis, suggesting the possibility of its origin from ectopic rete testis epithelium. This marks the inaugural documentation in the English literature of an SC within the testis found incidentally during castration for prostatic cancer.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 88%

mentioning

confidence: 99%

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A Simple Cyst of the Testis was Found Incidentally during Castration for Prostatic Cancer

Tachibana,

Hamayasu,

Nakagawa

et al. 2023

Preprint

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“…3 Testis tümörünü taklit edebilir. 5 Brusellada görülen granülomatöz inflamasyon, fokal nekrotik alanlar sonografik olarak tümörle ortak özellik gösterir. 6 Yine aynı şekilde brusellada görülen hipoekoik alan ile seminomda ultrasonografik olarak düzgün sınırlı hipoekoik fokal lezyon ortak özellik gösterir.…”

Section: Tartişma Ve Sonuçunclassified

“…En sık olarak tübüler şekilde, tubuluslar içinde eozinofilik ya da vakuollü sitoplazmalı, veziküler çekirdekli histiositler ve seyrek olarak gözlenen dev hücreler de içeren karakteristik granülomatöz lezyonlar görülür. 5,10 Tedavide rifampisin+doksisiklin, streptomi-sin+doksisiklin ve ofloksasin+rifampisin kombinasyonları kullanılmaktadır. 9 Sonuç olarak, özellikle tümör belirteçleri negatif olup testiste kitle saptanan olgularda, bruselloz gibi granülamatöz hastalıklarda akılda tutulmalıdır.…”

Section: Tartişma Ve Sonuçunclassified