Successful Detection and Removal of a Functional Parathyroid Adenoma in a Pony Using Technetium Tc 99m Sestamibi Scintigraphy

Tomlinson, Joy E.; Johnson, Amy L.; Ross, Michael W.; Engiles, Julie B.; Levine, David G.; Wisner, W.A.; Sweeney, R. W.

doi:10.1111/jvim.12285

Cited by 19 publications

(66 citation statements)

References 15 publications

(21 reference statements)

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“…; Tomlinson et al . ). In other reported cases of primary hyperparathyroidism in horses, no tumours or other sources of PTH were identified (Roussel and Thatcher ; Frank et al .…”

Section: Discussionmentioning

confidence: 97%

“…In the horse of the current report, the focal region of reduced radiopharmaceutical clearance at the level of the thoracic inlet 4 h after injection of 99m Tc‐sestamibi is consistent with the post mortem examination finding of a parathyroid adenoma at the thoracic inlet, similar to the scintigraphic findings of Tomlinson et al . ().…”

Section: Discussionmentioning

confidence: 97%

“…In contrast, Tomlinson et al . () identified a parathyroid adenoma at the thoracic inlet of a 20‐year‐old Welsh pony gelding using 99m Tc‐sestamibi scintigraphy and ultrasonography, and successful surgical removal and resolution of clinical and laboratory abnormalities attributed to primary hyperparathyroidism was achieved. In the horse of the current report, the focal region of reduced radiopharmaceutical clearance at the level of the thoracic inlet 4 h after injection of 99m Tc‐sestamibi is consistent with the post mortem examination finding of a parathyroid adenoma at the thoracic inlet, similar to the scintigraphic findings of Tomlinson et al .…”

Section: Discussionmentioning

confidence: 99%

“…; Tomlinson et al . ). This report describes the presentation, clinicopathological findings, diagnostic procedures, treatment and outcome in a pony with primary hyperparathyroidism due to a functional parathyroid adenoma.…”

Section: Introductionmentioning

confidence: 97%

“…; Tomlinson et al . ) or parathyroid hyperplasia (Toribio ), or may be idiopathic (Roussel and Thatcher ; Frank et al . ).…”

Section: Introductionmentioning

confidence: 99%

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Primary hyperparathyroidism in a 17‐year‐oldArab ×WelshCob pony mare with a functional parathyroid adenoma

Cottle

Hughes

Thompson

et al. 2014

Equine Veterinary Education

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Summary Primary hyperparathyroidism was identified in a 17‐year‐old Arab × Welsh Pony mare that experienced weight loss for 6 months and was presented with mild facial asymmetry, right forelimb lameness and weight shifting amongst all limbs. Osteodystrophia fibrosa was demonstrated on radiographic examination of the head and there was radiographic evidence of osteopenia of the appendicular skeleton. The horse had persistent hypercalcaemia (4.0 mmol/l), hypophosphataemia (0.59 mmol/l) and an increased concentration of circulating parathyroid hormone (1401 pg/ml). On scintigraphic examination, a subjective focal increase in uptake of 99mtechnetium‐sestamibi was identified in the right thyroid gland and at the thoracic inlet in delayed images. Surgical exploration of the thyroid region was unrewarding, whereas surgery at the thoracic inlet was not undertaken. One year later, the horse developed a pathological fracture of the third metacarpal bone and was subjected to euthanasia. At post mortem examination, a parathyroid adenoma was found at the level of the thoracic inlet adjacent to the trachea. Gross and histological examination also confirmed severe osteodystrophia fibrosa and osteopenia.

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“…; Tomlinson et al . ). In other reported cases of primary hyperparathyroidism in horses, no tumours or other sources of PTH were identified (Roussel and Thatcher ; Frank et al .…”

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 97%

“…; Tomlinson et al . ) or parathyroid hyperplasia (Toribio ), or may be idiopathic (Roussel and Thatcher ; Frank et al . ).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations