Subungual Squamous Cell Carcinoma. Presentation of two Cases

Vázquez, María José Domínguez; Amayuelas, Ramón Navarra; Martin-Urda, M.T.; Fernández, C. Abellaneda; Tapia, Gustavo

doi:10.1016/s1578-2190(10)70694-6

Cited by 3 publications

(1 citation statement)

References 13 publications

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“…Diagnosis of subungal SCC is inherently difficult, because of its resemblance to a variety of benign conditions, such as viral warts, onychomycosis, paronychia, glomus tumours, ingrowing nail, pyogenic granuloma, subungual exostosis, chronic osteomyelitis, traumatic dyschromia, keratoacanthomas and melanotic naevi. [5,9,10]. For this reason, its diagnosis may be easily missed or delayed.…”

Section: Case Reportmentioning

confidence: 99%

Subungual Squamous Cell Carcinoma Masquerading as an Onychomycosis

Sever¹

2012

Ann Clin Anal Med

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ÖzetTırnağın tümörleri iyi veya habis nitelikte olabilir. Tırnağa ait tümörlerin değişik histolojik tipleri literatürlerde rapor edilmiştir. Tırnağın yassı epitel hücreli karsinomu oldukça nadirdir ve yanlış tanı konulmaktadır. Bu nedenle bu tümörün insidansını belirlemek oldukça güçtür. Biz bu olgu sunumunda yanlış tanı konulan ve bu yüzden tedavide gecikmeye neden olan tırnağın yassı epitel hücreli karsinomunu sunmayı hedefledik. Tırnak lezyonları, tedavide gecikmeye neden olmamak için dikkatlice incelenmeli ve gerekirse bu lezyonlar histopatolojik olarak incelenmelidir. Histopatolojik tanıya göre uygun tedavi planlanmalıdır. Anahtar KelimelerOnikomikoz; Yassı Epitel Hücreli Karsinoma; Tırnak Yatağı Tümörleri Abstract Tumors of nail unit may be benign or malign. Different histological variants of subungual tumours have been reported. Subungual squamous cell carcinoma is rare, and the disease is often misdiagnosed as a benign condition, therefore it is difficult to estimate the real incidence of this disease. We hereby present a case of subungual squamous cell carcinoma that has previously been treated as leading to a delay in diagnosis and treatment. For this reason, the nail unit changes should be examined carefully and the diagnosis should be done with the histopathological examinations. Proper treatment should be planned according to the histopathological diagnosis.

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Section: Case Reportmentioning

confidence: 99%

Subungual Squamous Cell Carcinoma Masquerading as an Onychomycosis

Sever¹

2012

Ann Clin Anal Med

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Marjolin’s squamous cell carcinoma of the hallux following recurrent ingrown toenail infections

2017

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Marjolin's squamous cell carcinoma (SCC) affecting the toe is rare. Due to resemblance with benign conditions it can often result in misdiagnosis. We report a case of Marjolin's SCC affecting the proximal hallux in a patient with recurrent ingrown toenail infections. A 58-year-old woman with a background of wedge resections for ingrown toenail and distal phalanx amputation for osteomyelitis presented with pain and hyperkeratotic raised ulcer around the proximal phalanx. MRI scan revealed soft tissue mass infiltrating the proximal phalanx with biopsies confirming a SCC. The patient underwent first ray amputation and made a good clinical recovery and remains disease free. Due to clinical similarities with benign conditions, awareness of Marjolin's SCC as a potential diagnosis when treating patients with recurrent ingrown toenail is imperative. We recommend patients with recurrent ingrown toenail or ulceration with a background of chronic infection have biopsies performed to exclude potential malignancy.

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Early diagnosis of subungual squamous cell carcinoma of the hallux

Kakşi

Özdemır²,

Balevi³

et al. 2015

Dermatology Online Journal

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Primary subungual squamous cell carcinoma (SCC) of the toe is rare in the literature and frequently late or misdiagnosed. Lack of awareness among physicians of the specific clinical findings, the indolent course of the disease, and the high prevalence of benign conditions of the nail unit may account for delays in diagnosis. In addition to difficulties in identifying the true incidence of this tumor, a standardized therapeutic approach does not currently exist. We present a case of subungual SCC of the first toe without bone invasion. The tumor was diagnosed early, treated with conservative surgical excision, and showed no recurrence or metastasis after 2 years of follow-up.

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Subungual Squamous Cell Carcinoma. Presentation of two Cases

Cited by 3 publications

References 13 publications

Subungual Squamous Cell Carcinoma Masquerading as an Onychomycosis

Subungual Squamous Cell Carcinoma Masquerading as an Onychomycosis

Marjolin’s squamous cell carcinoma of the hallux following recurrent ingrown toenail infections

Early diagnosis of subungual squamous cell carcinoma of the hallux

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