a b s t r a c tBio-compatible composite particles composed of hydroxyapatite (Ca 10 (PO 4 ) 6 (OH) 2 , HAp) and ferrite (maghemite (␥-Fe 2 O 3 ) or magnetite (Fe 3 O 4 )) were synthesized by two-step synthesis. In this work, coprecipitation method using aqueous solution of FeSO 4 and FeCl 3 was employed to synthesize ␥-Fe 2 O 3 and Fe 3 O 4 particles. It was found that the resultant phase was changed by the molar ratio of FeSO 4 and FeCl 3 , and optimal molar ratio to suppress the coexistence of ␣-FeOOH was FeSO 4 /FeCl 3 = 2. The suspension composed of crushed ferrite particles, Ca(NO 3 ) 2 and H 3 PO 4 aqueous solution with surfactant ultrasonically nebulized into mist and the mist was pyrolyzed at 500 • C to synthesize HAp-ferrite composite particles. The shape of the synthesized composite particle was round with dimple, and the particle size was around 0.5-3 m in diameter. The composite particle showed saturation magnetization of 0.833 emu/g. Net saturation magnetization of the ferrite component was calculated to be 46.4 or 48.0 emu/g under the assumption that the ferrite was composed of ␥-Fe 2 O 3 or Fe 3 O 4 , respectively.