Substituted methanes

Synthetic routes for a variety of halogenated (chiral) acetic acids from diethyl malonate

“…They serve as precursors to halomethanes, specically CHBrClF, [20][21][22][23] CHBrFI, 24 and isotopically chiral CHDXY. [25][26][27][28] CHBrClF (7) itself has been subject to very early attempts to measure parity violation effects in molecules. 29 Since the prediction and experimental verication of the weak interaction in particle physics in around 1956/57, 30,31 it became immediately clear that this interaction also has consequences in chemistry: for an isolated enantiomer, racemization following R ¼ S leads to a tiny heat of reaction, D r H , in the order of 10 À15 kJ mol À1 (ref.…”

Raman Spectrometry

“…All show evidence of hydrogen bonding of the C-H of the chloroform (276). New measurements have been made of the Raman spectra of CH2C12, CHDC12, CD2C12 (256); CD2-BrCl, CHDBrCl (328); in another study of ten chlorinated and brominated methanes, satellite structure on certain bands in the chlorinated compounds is assigned to chlorine isotopic splitting (88). The spectra of polycrystalline CH3Br (139), and CH3I (138) have been measured at 77°K.…”