1983
DOI: 10.1016/s0022-5347(17)51780-2
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Subsequent Malignancies Associated With Carcinoma of the Uterine Cervix: Including an Analysis of the Effect of Patient and Treatment Parameters on Incidence and Sites of Metachronous Malignancies

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Cited by 5 publications
(7 citation statements)
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“…There is no unanimity in the literature concerning the coexistence of uterine cervix and breast cancers. Some of the authors pointed out the diminished risk of suffering from breast cancer after treatment for cervical cancer, which is explained by different etiological factors, different socio-economic status and loss of ovarian function after cervical cancer treatment [20,21]. However, other series of patients often indicate the coexistence of these cancers.…”
Section: Discussionmentioning
confidence: 99%
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“…There is no unanimity in the literature concerning the coexistence of uterine cervix and breast cancers. Some of the authors pointed out the diminished risk of suffering from breast cancer after treatment for cervical cancer, which is explained by different etiological factors, different socio-economic status and loss of ovarian function after cervical cancer treatment [20,21]. However, other series of patients often indicate the coexistence of these cancers.…”
Section: Discussionmentioning
confidence: 99%
“…However, other series of patients often indicate the coexistence of these cancers. The common aetiology in patients of cervical cancer is the reason for the increased risk of suffering from lung, esophagus, bladder and kidney cancers -tobacco related cancers and vulvar and rectal cancer -HPV related [14,[20][21][22]. Stopping smoking by the cancer patient can decrease the risk of suffering from a subsequent cancer of this aetiology.…”
Section: Discussionmentioning
confidence: 99%
“…Therapeutic irradiation can induce secondary malignancies within or at the margin of radiation field after a long latent period (7) . Patients after treatment for gynecological malignancies have a 3-6% lifetime risk of developing a second unrelated malignancy (8,9) . SCC of the genital tissue after radiotherapy is rarely seen and has been widely discussed.…”
Section: Discussionmentioning
confidence: 99%
“…The evidence for women undergoing a premature menopause is that they do not have an increase breast cancer risk but should instead continue HRT until the age of the natural menopause [102]. The concern that HRT usage will increase the risk of breast cancer in the treated cervical cancer population is therefore not grounded and some studies have actually indentified a reduced risk in this population [103,104], which is likely to be due to the effect of an early menopause.…”
Section: Second Malignanciesmentioning
confidence: 99%
“…Radiation-associated uterine malignancies are more likely to be of higher grade and stage as compared to spontaneous cancers and as a result carry a poorer prognosis [108]. Several studies have identified an increased association with a second primary lung malignancy [104,109], however this is likely to be a reflection of the smoking behaviour in this population and reinforces the importance of smoking cessation advice and support following a cervical cancer diagnosis.…”
Section: Second Malignanciesmentioning
confidence: 99%