Sublobar Resection in Stage IA Non–Small Cell Lung Cancer: Role of Preoperative CT Features in Predicting Pathologic Lymphovascular Invasion and Postoperative Recurrence

Abstract

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Imaging biomarkers to stratify lymph node metastases in abdominal CT – Is radiomics superior to dual-energy material decomposition?

“…The identification of patients with lymph node metastases is decisive and has therapeutic and prognostic relevance [32] , [33] . RECIST criteria give guidance, but follow-up scans may be necessary for diagnosis, potentially causing delayed detection of nodular spread or recurrence of disease.…”

18F-FDG PET/CT radiomics for prediction of lymphovascular invasion in patients with early stage non-small cell lung cancer

“…Lymphovascular invasion (LVI) refers to cancer cell occurrence in the endothelium-lined lumen or cancer cells-mediated lymphovascular wall destruction. LVI has been reported to occur only in partially solid nodes with a predominantly solid imaging presentation and solid nodes with a solid component of >10 mm (9). In an early-stage NSCLC with a solid imaging presentation, the 5-year recurrence rate increases among cancer cases showing pathological LVI (21.7%) compared with those with no pathological LVI (7.4%), considered a high-risk pathologic feature remarkably increasing relapse and lymph node metastasis incidence (10)(11)(12)(13)).…”

Meta-analysis of the relationship between lymphovascular invasion and prognosis of patients with stage I gastric cancer

“…[4][5][6] At present, several studies in other solid tumors have confirmed that lymphovascular invasion is closely related to the prognosis of many kinds of malignant tumors such as lung cancer, breast cancer, and esophageal cancer. [7][8][9] However, the relationship between lymphovascular invasion and the prognosis of patients with stage I gastric cancer is still controversial. One view is that lymphovascular invasion is an independent prognostic factor in patients with stage I gastric cancer, [10,11] while the other view is just the opposite.…”