“…Even at very low concentration heavy metals (Cu, Ni, Fe, Co, Mn, Cr, Zn, Hg, Cd, Pb) induce changes in morphology, physiological and biochemical parameters in fish. Such effects besides including decrease in immunity [7], changes in behavior, growth, digestive enzyme activities [2], efficiency of food assimilation [8], also affect state of carbohydrate metabolism [9][10][11]. However, little is known about the uptake of heavy metals through the skin.…”