Subjective and objective clinical outcomes of a new trifocal toric intraocular lens and effect of femtosecond laser cataract surgery

Dönmez, Oya; Asena, Bilgehan Sezgin; Akova, Yonca A.

doi:10.1177/11206721211046496

Cited by 6 publications

(5 citation statements)

References 30 publications

(115 reference statements)

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“…Notably, existing Panoptix Toric IOL cohort studies identify between 80% and 94.8% of patients achieving spectacle independence following surgery. [14][15][16][17][18][19] All findings within the retrospective study reflect a unilateral outcome. Given bilateral summation, it would be reasonably expected that binocular outcomes will also result in improved outcomes at all distances and would reflect real-world practice.…”

Section: Discussionmentioning

confidence: 90%

“…15 Donmez et al in 79 eyes indicated all eyes achieving 20/40 or better for both near and intermediate distances. 16 Kohnen et al similarly 4234 describe all eyes achieving this level of uncorrected near and intermediate visual acuity in their small cohort. 14 In the absence of significant differences in residual refractive error between cohorts, the difference at intermediate for our retrospective study is likely to reflect the variation across postoperative visit and assessment distance within the practices.…”

Section: Discussionmentioning

confidence: 96%

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Visual and Refractive Efficacy of Panoptix Toric Intraocular Lens in a Clinical Setting

Ackerman¹,

Lawless²,

Levitz³

et al. 2022

OPTH

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Trifocal Intraocular Lenses (IOLs) were developed to provide patients with effective near, intermediate and distance vision, thus minimizing spectacle dependency. Residual astigmatism has previously been shown to impact unaided visual acuity across all distances; therefore, to optimise the expected outcomes, consideration of preoperative corneal astigmatism is essential. The purpose of this study was to provide a real-world, multi-site review of visual and refractive outcomes in eyes undergoing implantation with the Panoptix Trifocal toric IOL platform. Patients and Methods: This study represents a two-fold approach. Patients who had previously undergone routine cataract removal and IOL insertion with the Panoptix Toric IOL were retrospectively analysed for routine efficacy and safety endpoints ("Retrospective Cohort"). Data was retrieved from the preoperative, surgical and postoperative visits (range 2-6 weeks). A further subset of patients undergoing lens removal and bilateral Panoptix Toric IOL insertion were identified at surgery ("Qualitative Cohort"). These patients underwent additional testing inclusive of quality of vision questionnaire and bilateral defocus curve. Results: A total of 466 eyes of 254 patients were included in the retrospective cohort. Between 91% and 98% of eyes, respectively, were within 0.50D and 1.00D of target. Mean absolute difference from Spherical Equivalent (SE) target was 0.22 ± 0.24Ds. Following surgery, 94% of eyes demonstrated a refractive astigmatism of 0.50D or less. Further, 61% eyes achieved uncorrected distance visual acuity (UDVA) of 20/20 or better, increasing to 94% achieving 20/32 or better. Seventy percent of eyes unilaterally achieved N5 unaided and 66.0% achieved N8 or better at intermediate. In the qualitative cohort, no patient described any symptom as significant or requested explant. Conclusion:In a real-world setting, the PanOptix toric trifocal IOL continues to demonstrate refractive accuracy and good visual performance at all focal distances. This IOL also exhibited good quality of vision, with minimally bothersome visual disturbances or photic phenomena.

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Section: Discussionmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 96%

Visual and Refractive Efficacy of Panoptix Toric Intraocular Lens in a Clinical Setting

Ackerman¹,

Lawless²,

Levitz³

et al. 2022

OPTH

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“…For example, Nicula et al cited a positive dysphotopsia rate of only 18.8% in their RLE patients, but their self-developed survey was limited and queried only about postoperative “halos and glittering” [ 19 ]. Another PanOptix study described only 1 out of 55 patients who reported “disturbing haloes,” but again their questionnaire was non-standardized, and their population included both RLE patients and patients with cataract [ 28 ]. In general, it is difficult to compare the frequency of reported visual disturbances amongst different PanOptix studies in the literature because of the variety of non-standardized questionnaires used.…”

Section: Discussionmentioning

confidence: 99%

Visual Outcomes and Patient Satisfaction After Bilateral Refractive Lens Exchange with a Trifocal Intraocular Lens in Patients with Presbyopia

et al. 2023

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Introduction Refractive lens exchange (RLE) patients represent a unique population with a different baseline and set of expectations compared to their cataract counterparts. Visual outcomes and patient satisfaction following RLE with bilateral implantation of a trifocal intraocular lens (IOL) were assessed in a cohort of patients with presbyopia and without cataract. Methods Charts of patients with presbyopia who underwent femtosecond laser-assisted RLE with bilateral implantation of the PanOptix trifocal IOL (toric and non-toric) at a single-surgeon, private practice center from September 2019 to August 2020 were retrospectively reviewed. Eyes with prior keratorefractive surgery, amblyopia, or underlying pathology were excluded. Primary endpoints included corrected and uncorrected visual acuity at distance (CDVA and UDVA), intermediate (DCIVA and UIVA), and near (DCNVA and UNVA) at 6 months. Secondary endpoints included residual refractive error, patient-reported satisfaction, spectacle independence, and visual disturbance profile as assessed by a validated questionnaire at 6 months. Results Seventy-eight eyes of 39 patients (mean age 56 ± 6 years; 79% female) were included. Most eyes were hyperopic (mean SE 2.35 ± 1.81). Postoperatively, 100% and 92% of eyes were within ± 1.00 D and ± 0.50 D of emmetropia, respectively. One hundred percent, 97%, and 97% of patients achieved UDVA, UNVA, and UIVA of logMAR 0.1 or better. Starbursts were the most frequent (67%) and bothersome (41%) visual disturbance cited, but nearly half (41%) of patients rated them as absent or “not bothersome at all.” Overall, 77% of patients reported achieving complete spectacle independence with 87% and 90% of patients stating they were satisfied with their vision and would recommend the same procedure to others, respectively. Conclusions RLE with bilateral implantation of the PanOptix IOL is a safe and effective procedure with good patient satisfaction. Because of their relatively clear native lenses and visually demanding needs compared to their cataract counterparts, surgeons should take extra precautions to counsel RLE patients on the limitations of trifocal technology. Supplementary Information The online version contains supplementary material available at 10.1007/s40123-023-00708-x.

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“…It demonstrates the accuracy of LenSx and the advantages of small tissue damage, without damaging the cornea, iris, and other capsule tissues of the lens, which also provides an effective location for subsequent IOL implantation. Donmez et al [33] reported that PanOp-tix trifocal toric IOL has excellent refractive stability and can provide excellent visual quality for patients.…”

Section: Discussionmentioning

confidence: 99%

Observation of Visual Quality after Femtosecond Laser-Assisted Cataract Surgery Combined with Trifocal Intraocular Lens Implantation

Ma¹,

Sun²,

Liu³

et al. 2022

Computational and Mathematical Methods in Medicine

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Objective. This study is the first observation of Alcon’s PanOptix trifocal intraocular lens (IOL) implanted in 55 cataract patients with femtosecond laser-assisted cataract surgery. Methods. Fifty-five patients (63 eyes) with cataract were treated with femtosecond laser-assisted cataract surgery combined with trifocal IOL implantation. Visual acuity, defocus curve, higher order aberration (HOA), refractive stability, eyeglass removal rate, and satisfaction were evaluated and analyzed. Results. We found that the visual acuity of patients with near, intermediate, and distance vision was better than 0.1 LogMAR at 1, 3, and 6 months after the completion of surgery. The uncorrected near visual acuity (UCNVA), uncorrected intermediate visual acuity (UCIVA), and uncorrected distance visual acuity (UCDVA) of patients at 1, 3, and 6 months after surgery were compared with those before operation, showing statistical significance. Six months after the operation, all patients’ surgical eyes had a smooth transition in the defocus range from +0D to -2.5D, and the visual acuity of the surgical eyes reached a level better than 0.1 LogMAR. The statistical results of 6-month follow-up showed that the eyeglass removal rate at near, intermediate, and far distances was 100%. At 6 months postoperatively, only 1 case had nocturnal glare, which affected life; 3 cases developed glare and halo but did not affect life. The patient satisfaction rate was 98.18%. Conclusions. Femtosecond laser-assisted cataract surgery with trifocal IOL implantation can remove the lens from the patient with satisfactory visual quality and significantly improve the postoperative satisfaction of the patient.

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Subjective and objective clinical outcomes of a new trifocal toric intraocular lens and effect of femtosecond laser cataract surgery

Cited by 6 publications

References 30 publications

Visual and Refractive Efficacy of Panoptix Toric Intraocular Lens in a Clinical Setting

Visual and Refractive Efficacy of Panoptix Toric Intraocular Lens in a Clinical Setting

Visual Outcomes and Patient Satisfaction After Bilateral Refractive Lens Exchange with a Trifocal Intraocular Lens in Patients with Presbyopia

Observation of Visual Quality after Femtosecond Laser-Assisted Cataract Surgery Combined with Trifocal Intraocular Lens Implantation

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