Visual and Refractive Efficacy of Panoptix Toric Intraocular Lens in a Clinical Setting

Abstract

Trifocal Intraocular Lenses (IOLs) were developed to provide patients with effective near, intermediate and distance vision, thus minimizing spectacle dependency. Residual astigmatism has previously been shown to impact unaided visual acuity across all distances; therefore, to optimise the expected outcomes, consideration of preoperative corneal astigmatism is essential. The purpose of this study was to provide a real-world, multi-site review of visual and refractive outcomes in eyes undergoing implantation with the Panoptix Trifocal toric IOL platform. Patients and Methods: This study represents a two-fold approach. Patients who had previously undergone routine cataract removal and IOL insertion with the Panoptix Toric IOL were retrospectively analysed for routine efficacy and safety endpoints ("Retrospective Cohort"). Data was retrieved from the preoperative, surgical and postoperative visits (range 2-6 weeks). A further subset of patients undergoing lens removal and bilateral Panoptix Toric IOL insertion were identified at surgery ("Qualitative Cohort"). These patients underwent additional testing inclusive of quality of vision questionnaire and bilateral defocus curve. Results: A total of 466 eyes of 254 patients were included in the retrospective cohort. Between 91% and 98% of eyes, respectively, were within 0.50D and 1.00D of target. Mean absolute difference from Spherical Equivalent (SE) target was 0.22 ± 0.24Ds. Following surgery, 94% of eyes demonstrated a refractive astigmatism of 0.50D or less. Further, 61% eyes achieved uncorrected distance visual acuity (UDVA) of 20/20 or better, increasing to 94% achieving 20/32 or better. Seventy percent of eyes unilaterally achieved N5 unaided and 66.0% achieved N8 or better at intermediate. In the qualitative cohort, no patient described any symptom as significant or requested explant. Conclusion:In a real-world setting, the PanOptix toric trifocal IOL continues to demonstrate refractive accuracy and good visual performance at all focal distances. This IOL also exhibited good quality of vision, with minimally bothersome visual disturbances or photic phenomena.

Clinical Performance of an Omnidirectional Aberration-Free Trifocal Toric Intraocular Lens

“…This correlates with the visual acuities obtained at distance, intermediate and near vision (see Table 2 ). Ackerman et al 20 in a sample of 254 patients implanted with the AcrySof IQ PanOptix toric IOL at 3 months of follow-up reported that this lens achieved good visual acuity across all distance with mean visual acuity greater than 0.1 logMAR for defocus levels between −2.50D and +1.00D with the exception of −1.00D and −0.50D steps.…”

“…They also found that of the 25 patients of their sample, 76% reported halos, 52% glare, 16% starbursts, 8% ghosting, and 8% distorted vision. Ackerman et al 20 included a quality of vision questionnaire at the 3 months follow-up and indicated that the most frequent and severe phenomena were starbursts, halos and glare. They indicated that the impact of the phenomena on daily activities is of equal importance however and the responses indicated only glare was described to be “quite a bit” bothersome (2 patients).…”

Prospects for the Use of Monofocal IOLs with Extended Depth of Focus (EDOF) Instead of Traditional Multifocal (Trifocal) IOLs in Cataract Surgery

“…ИОЛ выполнена из гидрофобного мягкого акрила с УФ-фильтром, число Аббе -55, имеет заднюю ахроматическую дифракционную поверхность для усиления восприятия контрастности и эшелетт дизайн, который позволяет продлевать диапазон фокуса света [10][11][12]. В качестве сравнительных оценивались, в большинстве случаев, традиционные ТФИОЛ («PanOptix», «FineVison» и «Lisa tri 839MP») [13][14][15]. Во всех исследованиях, включенных в данный обзор, была выполнена двусторонняя имплантация.…”