Subgingival Microflora in Turkish Patients with Periodontitis

Dogan, Belgin; Antinheimo, Johanna; Çetiner, Deniz; Bodur, Ayşen; Emingil, Gülnur; Buduneli, Eralp; Uygur, C; Fıratlı, Erhan; Lakio, Laura; Asikainen, Sirkka

doi:10.1902/jop.2003.74.6.803

Cited by 49 publications

(88 citation statements)

References 62 publications

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“…Data from earlier investigations in Chinese, African and Hispanic populations are also in accord with these findings (2,8,29,33). In contrast, A. actinomycetemcomitans was detected in much lower frequency in Japanese, Turkish, Swedish and American subjects (10,11,15,37). Although different methodologies were employed in these investigations, they clearly demonstrated that the prevalence rates of this pathogen seem to vary among ethnic groups with various periodontal status.…”

Section: Discussionsupporting

confidence: 80%

Prevalence of leukotoxic genotypes of Actinobacillus actinomycetemcomitans in Brazilians with chronic periodontitis

Rosalem¹,

Andrade²,

Colombo³

2006

Braz. J. Microbiol.

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Actinobacillus actinomycetemcomitans is considered a major etiologic agent of aggressive periodontitis but this species has also been associated with other forms of periodontal disease. Further, highly leukotoxic strains are related to severity of disease. This investigation determined the prevalence of A. actinomycetemcomitans and the occurrence of the leukotoxin gene 530-bp deletion in Brazilian subjects with chronic periodontitis. Twenty periodontally healthy and 20 chronic periodontitis subjects were selected. Fullmouth clinical examination was carried out at 6 sites/tooth. Subgingival biofilm samples were collected from the 3 deepest sites and 3 healthy sites from periodontitis subjects, as well as from 3 sites of individuals with periodontal health. A. actinomycetemcomitans and the genetic deletion were determined by the polymerase chain reaction. Significant differences were sought by Mann-Whitney, Chi-square, and Wilcoxon sign tests. Periodontitis subjects presented a higher prevalence (75%) of A. actinomycetemcomitans than individuals with health (45%) (p = 0.053). A mean frequency of 57.5% of A. actinomycetemcomitans -positive sites was observed in the periodontitis group. Of those, 75% were diseased, whereas 40% were healthy sites (p = 0.0001). Healthy subjects showed a mean frequency of 35% of positive sites. In contrast, the genetic deletion was detected only in 4 diseased sites from 2 chronic periodontitis patients. A high prevalence of A. actinomycetemcomitans was observed in Brazilians with chronic periodontitis. However, the leukotoxin gene 530-bp deletion was rarely detected in the subgingival biofilm of these subjects.

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Section: Discussionsupporting

confidence: 80%

Prevalence of leukotoxic genotypes of Actinobacillus actinomycetemcomitans in Brazilians with chronic periodontitis

Rosalem¹,

Andrade²,

Colombo³

2006

Braz. J. Microbiol.

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“…Estudios realizados en diferentes latitudes han reportado que A. actinomycetemcomitans es el más frecuente (en altas concentraciones) en periodontitis agresiva, especialmente en Rumania (6), Turquía (27), Tailandia (46), Corea (47) y Holanda (48). Resultados similares se encontraron en Norte América, aunque con menor frecuencia (15).…”

Section: Discussionunclassified

“…En consecuencia, la técnica del cultivo continúa siendo una herramienta útil en este tipo de estudios siempre y cuando se realice en condiciones óptimas (selección apropiada del sitio de la muestra, método utilizado para la recolección de la muestra, transporte, atmósfera, sistema de incubación, utilización de medios selectivos, empleo de pruebas bioquímicas adicionales para la determinación de especie e interpretación de los datos obtenidos) (40 (27).…”

Section: Discussionunclassified

“…Los microorganismos más frecuentemente aislados de la bolsa periodontal han sido muy estudiados en Norte América (7,11,(14)(15)(16)(17)(18)(19) y Europa (20)(21)(22)(23). Sin embargo, el perfil microbiológico de la periodontitis en poblaciones de Asia (24)(25)(26)(27), África (12,(28)(29)(30), Centro (31) y Sur América (32-37) parece diferir en frecuencia y composición debido, en parte, al frecuente hallazgo de microflora no usual. Por ejemplo, los bacilos entéricos de las familias Enterobacteriaceae y Pseudomonadaceae producen factores de virulencia que podrían afectar el comportamiento clínico de la periodontitis, así como su control y tratamiento.…”

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Microflora subgingival en periodontitis crónica y agresiva en Bogotá, Colombia: un acercamiento epidemiológico

et al. 2007

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Introducción. Los microorganismos involucrados en la periodontitis varían en cada región dependiendo de diferentes factores. Por ello cada país debe establecer su propio perfil microbiológico con el objeto de proponer esquemas adecuados de prevención y tratamiento. Objetivo. Investigar la presencia y concentración subgingival de Porphyromonas gingivalis, Tannerella forsythia, Actinobacillus actinomycetemcomitans, Prevotella intermedia/Prevotella nigrescens, Eikenella corrodens, Campylobacter rectus, Micromonas micros, Fusobacterium spp, Dialister pneumosintes y bacilos entéricos en pacientes con periodontitis en una población colombiana considerando edad, género y nivel socioeconómico. Materiales y métodos. Participaron 183 pacientes: 84 con periodontitis crónica, 59 con periodontitis agresiva y 40 individuos sanos. De cada paciente se obtuvo un grupo de muestras de los seis sitios con mayor profundidad de bolsa que se procesaron por cultivo para el aislamiento e identificación de las bacterias. Resultados. En periodontitis crónica y agresiva se detectaron con alta y similar frecuencia P. gingivalis, T. forsythia, P. intermedia/P. nigrescens, C. rectus, Fusobacterium spp y E. corrodens y con menor y similar frecuencia, M. micros, A. actinomycetemcomitans, D. pneumosintes y bacilos entéricos, principalmente de la tribu Klebsielleae. En los sujetos sanos se encontraron con frecuencia elevada P. intermedia/P. nigrescens, C. rectus y Fusobacterium spp y con frecuencia moderada, M. micros y E. corrodens. Conclusión. Los resultados indican que P. gingivalis, T. forsythia, P. intermedia/P. nigrescens, C. rectus, Fusobacterium spp y E. corrodens constituyen parte importante del perfil microbiológico de las periodontitis en la población colombiana. En la periodontitis agresiva, P. gingivalis se encontró más frecuentemente que A. actinomycetemcomitans.Palabras clave: periodontitis/epidemiología, Porphyromonas gingivalis, bacterias anaerobias, Enterobacteriaceae, Pseudomonadaceae.Subgingival microbiota in chronic and aggressive periodontitis in Bogotá, Colombia: an epidemiological approach Introduction. Periodontitis-associated microbiotas differ in regions around the world and vary with a variety of factors. This suggests that each country must establish its own dental microbiobiotic profile in order to formulate adequate prevention measures and more specific treatments. Objective. The prevalence and proportions of the following microorganisms were investigated: Porphyromonas gingivalis, Tannerella forsythia, Actinobacillus actinomycetemcomitans, Prevotella intermedia/Prevotella nigrescens, Eikenella corrodens, Campylobacter rectus, Micromonas micros, Fusobacterium spp, Dialister pneumosintes and enteric rods. The patients selected had been diagnosed with chronic periodontitis and aggressive periodontitis from clinical populations in Bogotá, Colombia. The variables of age, gender and socioeconomic level were included in the comparisons. Materials and methods. 183 patients were classified in two groups, chronic periodontit...

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“…Many cycles of exacerbation and remission may continue till the alveolar bone is destroyed and the teeth lost . Table 3 lists some of the species most frequently associated with periodontal diseases (Botero et al, 2007;Casarin et al, 2010;Dogan et al, 2003, Gajardo et al, 2005Kumar et al, 2003;Teixeira et al, 2006;Riep et al, 2009). Species associated with chronic periodontitis are predominantly Gram-negative with few Gram-positive anaerobes.…”

Section: Plaque In Chronic Periodontitismentioning

confidence: 99%

The Microbial Aetiology of Periodontal Diseases

Africa¹

2012

Periodontal Diseases - A Clinician's Guide

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Subgingival Microflora in Turkish Patients with Periodontitis

Cited by 49 publications

References 62 publications

Prevalence of leukotoxic genotypes of Actinobacillus actinomycetemcomitans in Brazilians with chronic periodontitis

Prevalence of leukotoxic genotypes of Actinobacillus actinomycetemcomitans in Brazilians with chronic periodontitis

Microflora subgingival en periodontitis crónica y agresiva en Bogotá, Colombia: un acercamiento epidemiológico

The Microbial Aetiology of Periodontal Diseases

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