Subependymomas: An analysis of Clinical and Imaging Features

Ragel, Brian T.; Osborn, Anne G.; Whang, Kum; Townsend, Jeannette J.; Jensen, Randy L.; Couldwell, William T.

doi:10.1227/01.neu.0000209928.04532.09

Cited by 114 publications

(120 citation statements)

References 35 publications

(50 reference statements)

Supporting

Mentioning

109

Contrasting

Unclassified

Order By: Relevance

“…They characteristically affect middle-aged and elderly men, and are preferently located at the fourth ventricle (50-60%), followed by the lateral ventricle (30-40%), septum pellucidum, third ventricle and spinal chord 11,13 . The natural history of subependymomas has not been well defined, but …”

Section: Discussionmentioning

confidence: 99%

“…The radiological characteristics of subependymomas are non-specific, making a definite preoperative diagnosis difficult. Aggressive features such as peritumoral vasogenic edema, mass effect, hemorrhage and dense enhancement indicating high vascularity are rare findings (12%) 11 . Overall ten cases of a subependymoma presenting with a hemorrhagic event have been reported in the literature (table 1).…”

Section: ; 21mentioning

confidence: 99%

“…During the surgical management of a hemorrhagic subependymoma, the neurosurgeon must face two problems, namely hydrocephalus and tumoral removal, almost always being on the diagnostic suspicion of an aggressive neoplasm or a vascular malformation 6,11 . It is our opinion, coincident with the attitude sustained by most authors, that a prompt tumoral removal can solve immediately both problems, avoiding shunting procedures and preventing new hemorrhagic episodes.…”

Section: ; 21mentioning

confidence: 99%

“…They are characterized by a benign clinical course, the rate of symptomatic subependymoma being estimated in a 40% approximately 8,11 . Only exceptionally does this kind of tumor present an aggressive behaviour 13 .…”

mentioning

confidence: 99%

See 3 more Smart Citations

Spontaneous acute hemorrhage within a subependymoma of the lateral ventricle: successful emergent surgical removal through a frontal transcortical approach

Carrasco¹,

Pascual

Navas

et al. 2010

Neurocirugía

View full text Add to dashboard Cite

SummaryIntroduction. Subependymomas are benign neoplasms intimately related to the ventricular system which only exceptionally associate hemorrhagic events. We present neuroradiological and pathological evidences of intratumoral hemorrhage within a single case of subependymoma operated on at our institution. Additionally we analyze retrospectively the well-defined reports of similar cases published in the scientific literature.Case report. ResumenIntroducción. Los subependimomas son neoplasias benignas que se desarrollan en estrecha relación con el sistema ventricular y que excepcionalmente asocian fenó-menos hemorrágicos. Describimos el caso de un subependimoma localizado en el ventrículo lateral que presentó una hemorragia intratumoral aguda de forma espontá-nea, como se evidenció en los estudios neurorradiológicos y patológicos realizados, incluyendo un análisis exhaustivo de los casos similares descritos en la literatura científica.Caso clínico. Se trata de un varón de 71 años que recibía tratamiento anticoagulante, y que presentó un cuadro brusco y progresivo de disminución del nivel de conciencia. Los estudios de neuroimagen evidenciaron la presencia de una masa localizada en el ventrículo lateral izquierdo, con signos de hemorragia reciente en su seno, que producía hidrocefalia biventricular aguda. La lesión fue resecada en su totalidad de forma urgente mediante un abordaje frontal transcortical. El estudio patológico de la lesión demostró que se trataba de un subependimoma con focos hemorrágicos. En el periodo postoperatorio, el paciente presentó un déficit de memoria global, tanto anterógrada como retrógrada.Conclusiones. Los episodios de hemorragia espontánea aguda constituyen un fenómeno excepcional en el caso de los tumores de histología benigna como los subependimomas, y pueden transformar un curso clínico asintomático en una emergencia quirúrgica debido al desarrollo de hidrocefalia aguda. La extirpación completa de la lesión de forma urgente representa la opción de manejo quirúrgico más apropiada, ya que permite un reestablecimiento inmediato de la circulación de líquido cefalorraquídeo y previene la aparición de resangrado.PALABRAS CLAVE: Prosencéfalo basal. Región septal. Subependimoma. Tumor cerebral hemorrágico. Ventrículo lateral.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: ; 21mentioning

confidence: 99%

Section: ; 21mentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Spontaneous acute hemorrhage within a subependymoma of the lateral ventricle: successful emergent surgical removal through a frontal transcortical approach

Carrasco¹,

Pascual

Navas

et al. 2010

Neurocirugía

View full text Add to dashboard Cite

show abstract

“…Given their indolent nature, surgery should err on the side of caution i.e. on leaving tumour behind rather than causing a neurological deficit (Ragel et al, 2006).…”

Section: Ependymomamentioning

confidence: 99%

Neurosurgical Management of Gliomas

Werndle¹,

Jones²,

Papadopoulos³

2011

Diagnostic Techniques and Surgical Management of Brain Tumors

View full text Add to dashboard Cite

Surgical management of subependymoma in a cat

Sakamoto

Chambers

Fujimoto³

et al. 2022

Vet Record Case Reports

View full text Add to dashboard Cite

A 10‐year‐old, domestic shorthair cat was presented with a 7‐month history of anorexia and 2‐month history of severe obtundation. Neurological examination revealed proprioceptive ataxia and decreased postural reactions in the four limbs. On magnetic resonance imaging, a contrast‐enhanced mass lesion dorsal to the obex region was found, causing cerebellar and brainstem compression. The mass was aspirated by an ultrasonic aspirator and complete removal was achieved. After surgery, the mental status and appetite of the cat was markedly improved. On histopathological examination, the mass was diagnosed as subependymoma. The cat was neurologically normal, and no recurrence was observed on magnetic resonance imaging 3 months postoperatively. There was no evidence of clinical recurrence at 8 month postoperative follow‐up by telephone interview. This is the first description of surgical management of subependymoma in a cat. Subependymoma is a benign tumour in cats, and the prognosis is expected to be good after surgical management as reported in humans.

show abstract

Subependymomas: An analysis of Clinical and Imaging Features

Cited by 114 publications

References 35 publications

Spontaneous acute hemorrhage within a subependymoma of the lateral ventricle: successful emergent surgical removal through a frontal transcortical approach

Spontaneous acute hemorrhage within a subependymoma of the lateral ventricle: successful emergent surgical removal through a frontal transcortical approach

Neurosurgical Management of Gliomas

Surgical management of subependymoma in a cat

Contact Info

Product

Resources

About