2021
DOI: 10.1016/j.jse.2020.11.018
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Subcutaneous tissue disinfection significantly reduces Cutibacterium acnes burden in primary open shoulder surgery

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Cited by 9 publications
(4 citation statements)
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“…40 However, a recent prospective clinical trial underlined the importance of the additional disinfection of the subcutaneous tissue with povidone-iodine solution after skin incision as the authors demonstrated a significant reduction in contamination of the surgical field with C acnes. 38 The incapacity of systemic antibiotics to permanently eliminate C acnes, together with the additional shortcoming of creating resistant germs, 14 led to the introduction of topical agents for the treatment of acne vulgaris. BPO was introduced for its bactericidal effect on C acnes 16 through free oxygen radical mechanisms 6 by avoiding wound healing problems.…”
Section: Discussionmentioning
confidence: 99%
“…40 However, a recent prospective clinical trial underlined the importance of the additional disinfection of the subcutaneous tissue with povidone-iodine solution after skin incision as the authors demonstrated a significant reduction in contamination of the surgical field with C acnes. 38 The incapacity of systemic antibiotics to permanently eliminate C acnes, together with the additional shortcoming of creating resistant germs, 14 led to the introduction of topical agents for the treatment of acne vulgaris. BPO was introduced for its bactericidal effect on C acnes 16 through free oxygen radical mechanisms 6 by avoiding wound healing problems.…”
Section: Discussionmentioning
confidence: 99%
“…Moor et al 16 examined the benefit of subcutaneous disinfection to reduce C. acnes positive cultures in a 2:1 RCT of patients undergoing primary open deltopectoral shoulder surgery. After skin incision, the subcutaneous layer was treated with povidone-iodine solution in the disinfection group, and culture swabs were then taken from the deeper surgical field.…”
Section: Shoulder Arthroplastymentioning
confidence: 99%
“…Diagnosis of C. acnes infection, however, is challenging. Apart from its sometimes ambiguous clinical presentation, microbiological case definition is especially hampered by the ubiquitous presence of C. acnes , making the species also a common contaminant even of deep tissue specimens and despite appropriate skin disinfection measures ( 15 17 ). Moreover, recent research indicates that isolation of C. acnes even in high colony counts from prosthetic material of the shoulder does not necessarily correlate with symptomatic infection.…”
Section: Introductionmentioning
confidence: 99%