Subcorneal pustular dermatosis and crippling arthritis

Olsen, T. G.

doi:10.1001/archderm.115.2.185

Cited by 11 publications

(5 citation statements)

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“…In addition to these cutaneous manifestations, there have been lots of articles which presented specific or characteristic skin manifestations associated with RA, such as pyoderma gangrenosum (5)(6)(7)(8), Sjogren's syndrome (3,12), Sweet's syndrome (26,27), Mondor disease (28), cutaneous amyloidosis (29), erythema elevatum diutinum (30), and autoimmune bullous disorders. Several case reports describing skin lesions associated with RA have also been presented (31)(32)(33).…”

Section: Cutaneous Manifestation and The Association With Class Omentioning

confidence: 99%

Skin Manifestations Associated with Rheumatoid Arthritis

Yamamoto

Ohkubo

Nishioka

1995

The Journal of Dermatology

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We examined cutaneous manifestations of rheumatoid arthritis (RA) of 142 Japanese patients who visited both the Departments of Dermatology and Rheumatology of our hospital. We classified cutaneous lesions into specific and/or characteristic or nonspecific ones. Nonspecific lesions predominated in our series. Among the specific skin manifestations, which comprised 10% of the total, rheumatoid nodules, rheumatoid papules, rheumatoid neutrophilic dermatitis, and severe vasculitic ulcers correlated with high titers of rheumatoid factors and progression of RA, while purpura and livedo did not. Nonspecific skin manifestations failed to correspond with the level of rheumatoid factors. Among the nonspecific lesions, asteatotic eczema, candida interdigitalis, and tinea unguium were commonly detected.

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Section: Cutaneous Manifestation and The Association With Class Omentioning

confidence: 99%

Skin Manifestations Associated with Rheumatoid Arthritis

Yamamoto

Ohkubo

Nishioka

1995

The Journal of Dermatology

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“…Other immunologic conditions that have shown association with SPD include IgG monoclonal paraproteinemia, 8 multiple myeloma, 9 and possibly an IgM monoclonal band. 10 In addition, other medical disorders have been noted in association with SPD including pyoderma gangrenosum; 11 systemic lupus erythematosus; 12 seropositive 10 and seronegative 13 rheumatoid arthritis; Crohn’s disease and ulcerative colitis; 14 synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome; 15 hyperthyroidism; 16 hypothyroidism; 17 apudoma; 18 and polycythemia rubra vera. 17…”

Section: Discussionmentioning

confidence: 99%

First presentation of Sneddon-Wilkinson disease with unexpected immunoglobulin A gammopathy: A case report and review of the literature

Mayba

Hawkins

2019

SAGE Open Medical Case Reports

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We present a case of Sneddon-Wilkinson disease in a 52-year-old female at her first presentation to dermatology. Outlined in the case are various investigations undertaken at this initial presentation, including rheumatologic and hematologic malignancy markers, which identified immunoglobulin A gammopathy. The systemic and topical therapies used to treat the patient’s condition are described, as well as her response to these treatments. In this discussion, we explain the epidemiology, pathophysiology, and clinical presentation of Sneddon-Wilkinson disease. Various medical conditions having known association with Sneddon-Wilkinson disease are discussed, including immunoglobulin A or immunoglobulin G monoclonal gammopathies and lymphoproliferative disorders. A comprehensive differential diagnosis for Sneddon-Wilkinson disease is provided, including immunoglobulin A pemphigus, acute generalized exanthematous pustulosis and pustular psoriasis, among others. We describe the systemic and topical therapy options for the treatment of Sneddon-Wilkinson disease, of which first line treatment is systemic dapsone. This patient serves as an excellent case of Sneddon-Wilkinson disease with unexpected immunoglobulin A gammopathy.

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“…SPD can also be associated with colitis ulcerosa, pyoderma gangrenosum [5], leukocytoclastic vasculitis, systemic lupus erythematosus [7]and rheumatoid-like arthritis [8]. …”

Section: Discussionmentioning

confidence: 99%

“…This dermatosis may be associated with a large number of diseases such as benign and malignant monoclonal gammopathies [1, 2, 3, 4, 5, 6], colitis ulcerosa, pyoderma gangrenosum [5], leukocytoclastic vasculitis, systemic lupus erythematosus [7]and rheumatoid-like arthritis [8]. …”

Section: Introductionmentioning

confidence: 99%

Subcorneal Pustular Dermatosis Treated with PUVA Therapy

Bauwens

Coninck²,

Roseeuw³

1999

Dermatology

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Background: Subcorneal pustular dermatosis (SPD) is a chronic recurrent pustular dermatosis of unknown etiology. Many treatments have been proposed, none of which has been uniformly successful. Objective: Our purpose is to report a patient with SPD successfully treated by PUVA and to review the literature concerning phototherapy treatment of SPD. Methods: A patient suffering from SPD resistant to diaminodiphenylsulphone (dapsone) responded well to a combination therapy consisting of dapsone and PUVA. He received 50 mg/day and 3 PUVA sessions a week. Photographs were taken at baseline and after 15 sessions. Results: The lesions were virtually cleared after 15 sessions. The patient remained free of lesions with a maintenance therapy of dapsone (50 mg/ day) and 1 PUVA session a week. Conclusion: The therapeutic value of phototherapy for the treatment of SPD still has to be confirmed and could be a valuable alternative for treatment-resistant patients.

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Subcorneal pustular dermatosis and crippling arthritis

Cited by 11 publications

References 0 publications

Skin Manifestations Associated with Rheumatoid Arthritis

Skin Manifestations Associated with Rheumatoid Arthritis

First presentation of Sneddon-Wilkinson disease with unexpected immunoglobulin A gammopathy: A case report and review of the literature

Subcorneal Pustular Dermatosis Treated with PUVA Therapy

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