Subchronic mild noise stress increases HRP permeability in rat small intestine in vitro

Bijlsma, P.B.; Raaij, M.T.M. van; Dobbe, C.J.G.; Timmerman, A.; Kiliaan, Amanda J.; Taminiau, J. A. J. M.; Groot, J.A.

doi:10.1016/s0031-9384(01)00424-3

Cited by 18 publications

(9 citation statements)

References 28 publications

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“…As these studies developed, it was hypothesized that sound stress changed intestinal permeability and was similar to systemic injection with LPS (Clark, et al 2004). While this was supported by other studies in the literature (Bijlsma, et al 2001) it was not definitively proven in this model. It could be said that the investigators using the CBA/J X DBA/2 model did not see these observations as strongly arguing against either self/non-self discrimination theory or its corollary, that lack of inherent suppression or limitation of the maternal immune system was the primary pathway by which resorptions occurred in this model.…”

Section: Introductionsupporting

confidence: 51%

To drive or be driven: the path of a mouse model of recurrent pregnancy loss

Bonney¹,

Brown²

2014

Reproduction

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Section: Introductionsupporting

confidence: 51%

To drive or be driven: the path of a mouse model of recurrent pregnancy loss

Bonney¹,

Brown²

2014

Reproduction

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“…In rodents, acute or subchronic stressors, including restraint stress, cold restraint stress, WAS, mild noise stress, and mixed restraint and acoustic stress, increased tissue conductance, and the fluxes of 3 H mannitol, 51 Cr-labeled EDTA, horseradish peroxidase, in the jejunum, ileum, and colon. 32,50,54,[69][70][71][72] These results indicate the ability of stress to modulate paracellular and transcellular transport of ions, and small and large macromolecules. Multiple mechanisms have been invocated to explain stress-mediated transport abnormalities.…”

Section: Permeabilitymentioning

confidence: 93%

Role of Corticotropin-releasing Factor in Gastrointestinal Permeability

Rodiño-Janeiro¹,

Alonso-Cotoner²,

Pigrau³

et al. 2015

J Neurogastroenterol Motil

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The interface between the intestinal lumen and the mucosa is the location where the majority of ingested immunogenic particles face the scrutiny of the vast gastrointestinal immune system. Upon regular physiological conditions, the intestinal microflora and the epithelial barrier are well prepared to process daily a huge amount of food-derived antigens and non-immunogenic particles. Similarly, they are ready to prevent environmental toxins and microbial antigens to penetrate further and interact with the mucosal-associated immune system. These functions promote the development of proper immune responses and oral tolerance and prevent disease and inflammation. Brain-gut axis structures participate in the processing and execution of response signals to external and internal stimuli. The brain-gut axis integrates local and distant regulatory networks and supersystems that serve key housekeeping physiological functions including the balanced functioning of the intestinal barrier. Disturbance of the brain-gut axis may induce intestinal barrier dysfunction, increasing the risk of uncontrolled immunological reactions, which may indeed trigger transient mucosal inflammation and gut disease. There is a large body of evidence indicating that stress, through the brain-gut axis, may cause intestinal barrier dysfunction, mainly via the systemic and peripheral release of corticotropin-releasing factor. In this review, we describe the role of stress and corticotropin-releasing factor in the regulation of gastrointestinal permeability, and discuss the link to both health and pathological conditions. (J Neurogastroenterol Motil 2015;21:33-50)

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“…Acute exposure to 95‐dB white noise as a mild stressor (Kioukia et al. , 2000; Bijlsma et al. , 2001) and a single exposure to the X‐maze, a well‐established animal test for anxiety (Handley & Mithani, 1984; Pellow et al.…”

Section: Introductionmentioning

confidence: 99%

“…Acute exposure to 95-dB white noise as a mild stressor (Kioukia et al, 2000;Bijlsma et al, 2001) and a single exposure to the X-maze, a well-established animal test for anxiety (Handley & Mithani, 1984;Pellow et al, 1985), respectively, were used in male rats to distinguish roughly between 5-HT release and behavioural responses induced by aversion or stress. under a 12-h light ⁄ dark schedule (light on at 06:00 h) with food and water freely available.…”

Section: Introductionmentioning

confidence: 99%

Anxiety but not arousal increases 5‐hydroxytryptamine release in the rat ventral hippocampus in vivo

Rex

Voigt

Fink

2005

Eur J of Neuroscience

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Central serotonin [5-hydroxytryptamine (5-HT)] is involved in the aetiology of numerous disease states, including depression and anxiety disorders. Studies have shown that exposure of rats to animal tests of anxiety increases extracellular 5-HT in the cortex or hippocampus determined by in vivo microdialysis. To discriminate whether this increase is caused by the aversive conditions of an animal test for anxiety or by an unconditioned stressor evoking mainly arousal, the present study investigates the effects of an unconditioned acoustic stimulus and exposure to the elevated plus maze (X-maze), respectively, on the release of 5-HT in the ventral hippocampus compared with hippocampal 5-HT release in the home cage and in a non-aversive unfamiliar environment in freely moving rats. Our results showed a distinct pattern of 5-HT release in the ventral hippocampus depending on the stimulus used. Exposure to the X-maze for 20 min was accompanied by an 'anxious' behaviour in the rats and increased extracellular 5-HT to 165% of basal release, whereas exposure to a less aversive 'deactivated' plus maze (115+/-6%) or to white noise for 20 min in the familiar surroundings of the home cage (98+/-6%) did not change hippocampal 5-HT release significantly, despite similar behavioural activation indicated by increased locomotor activity. While both the X-maze and white noise may model anxiety and stress to a certain extent, it seems that the X-maze is more aversive. The results suggest a close relationship between anxiety-related behaviour, but not arousal/non-specific behavioural activation, and 5-HT release in the ventral hippocampus.

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Subchronic mild noise stress increases HRP permeability in rat small intestine in vitro

Cited by 18 publications

References 28 publications

To drive or be driven: the path of a mouse model of recurrent pregnancy loss

To drive or be driven: the path of a mouse model of recurrent pregnancy loss

Role of Corticotropin-releasing Factor in Gastrointestinal Permeability

Anxiety but not arousal increases 5‐hydroxytryptamine release in the rat ventral hippocampus in vivo

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