Subacute thyroiditis in psoriasis patients treated with biologics targeting tumor necrosis factor‐α and interleukin‐17A, a report of two cases

Abstract

We report the first case of psoriasis patient who developed subacute thyroiditis during anti‐interleukin‐17 therapy. Ultrasonography of thyroid gland detected increased size with heterogeneous hypoechogenicity in both lobes on longitudinal section (Left panel, The distance between each dot is 1 cm). Cross section with color Doppler demonstrated substantial avascularity (Right panel).

The Risk of Systemic Diseases in Those with Psoriasis and Psoriatic Arthritis: From Mechanisms to Clinic

“…As anti-psoriatic biologic agents have the potential to reduce the systemic inflammation of psoriasis, we can suppose that using biologics could decrease the development of various autoimmune disorders. However, to date, there are only some case reports regarding the development of thyroiditis after using biologics in psoriasis [ 144 , 145 ]. However, the study by Kiguradze et al [ 143 ] reported that there was no significant association between the use of systemic anti-psoriatic biologics and the development of Hashimoto’s thyroiditis.…”