Su1290 – Efficacy and Safety of Lactobacillus Reuteri in Helicobacter Pylori Infection

Fonseca, Jana de Ameixa Valentim; Fernandes, Cristiane Cremiude Ribeiro; Cunha, Luı́s; Zung, Stevin

doi:10.1016/s0016-5085(19)38215-0

Cited by 3 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Fonseca J. и соавт. были проанализированы результаты 10 клинических ис следований, включающих антибактериальную терапию, дополненную препаратами из L. reuteri, при этом в де вяти исследованиях все группы комбинаций антибиоти ков и пробиотиков имели больший эрадикационный эф фект, чем при использовании только антибиотиков [101]. Sykora J. и соавт.…”

Section: анализ результатов исследований применения пробиотиков при H...unclassified

Mechanisms of microbial interactions between probiotic microorganisms and Helicobacter pylori

Isaeva,

Isaeva

2023

CMAC

View full text Add to dashboard Cite

Infection caused by Helicobacter pylori is currently one of the most common infection in the world, but the clinical picture can vary from asymptomatic manifestations to the development of stomach cancer. In order to eradicate the pathogen various regimens of antibacterial therapy have been proposed, but recent studies indicate a decrease in efficiency of this therapy due to the increasing rate of H. pylori resistance to antibiotics, the appearance of side effects, including the development of dysbiosis. One of the perspective directions of an alternative approach to the treatment of helicobacteriosis is probiotic therapy. The usage of probiotic therapy of H. pylori infection has two main directions. The first one is associated with the usage of probiotics to reduce the frequency of undesirable effects from the gastrointestinal tract during H. pylori antimicrobial therapy and the second one is the potentiation of the eradication effect due to the antagonistic effect on H. pylori. The purpose of this review was to summarize the latest data about the mechanisms of microbial interactions between probiotic microorganisms and H. pylori. The review examines the influence of H. pylori on the gastrointestinal microbiota, interspecific interactions of microorganisms in microbial consortia, mechanisms of antagonistic action of probiotic cultures on H. pylori, as well as the analysis of experience of using probiotics in the treatment of helicobacteriosis. At the same time, there will be many unresolved questions about the choice of the specific composition of the probiotic cocktail, dosage, duration of therapy, mechanisms of antimicrobial action of probiotics, as well as possible negative sides of this therapy, which requires further research.

show abstract

Section: анализ результатов исследований применения пробиотиков при H...unclassified

Mechanisms of microbial interactions between probiotic microorganisms and Helicobacter pylori

Isaeva,

Isaeva

2023

CMAC

View full text Add to dashboard Cite

show abstract

“…Although the use of probiotics alone has some effect, this approach does not meet the clinical needs, and use of probiotics as auxiliary in antibiotic therapy achieves greater significant effects [51]. Fonseca et al analyzed the results from ten clinical trials involving antibiotic therapy supplemented with different L. reuteri strains and all the antibiotic-probiotic combination groups exerted greater eradication effects than was realized with the single antibiotic group, with the exception of one study [83]. Sýkora et al treated 86 children with H. pylori infection and found that the eradication rate from the use of L. casei DN114001 along with triple therapy was 84.6%, while for the triple therapy group alone, it was 57.5%, and probiotic supplementation reduced the severity of the side effects simultaneously [84].…”

Section: Clinical Studiesmentioning

confidence: 99%

Using Probiotics as Supplementation for Helicobacter pylori Antibiotic Therapy

Yang

2020

IJMS

105

View full text Add to dashboard Cite

Helicobacter pylori is a well-known pathogen that is highly prevalent in the world population, and H. pylori infection is potentially hazardous to humans because of its relationship to various gastrointestinal diseases, such as gastric ulcers, chronic gastritis, and gastric carcinoma. Therefore, the clinical guidelines recommend taking antibiotic therapy to eradicate the pathogen, which usually leads to the desired therapeutic effect. However, some failure cases of this therapy indicate that the increasing antibiotic resistance and side effects may affect the therapeutic effect. Here we propose that using probiotics as supplementation for antibiotic therapy may provide an extra help. Recent studies have shown that probiotic supplementation therapy has promising application prospects; it can enhance the antibiotic effect to achieve a better therapeutic result and maintain the balance of the host gastrointestinal microbiota. In summary, under global conditions of increasing H. pylori prevalence, probiotic supplementation therapy is worthy of further studies for future clinical application.

show abstract

Probiotics in the treatment of Helicobacter pylori infection: reality and perspective

Исаева

Isaeva

2022

Minerva Gastroenterol

View full text Add to dashboard Cite

Su1290 – Efficacy and Safety of Lactobacillus Reuteri in Helicobacter Pylori Infection

Cited by 3 publications

References 0 publications

Mechanisms of microbial interactions between probiotic microorganisms and Helicobacter pylori

Mechanisms of microbial interactions between probiotic microorganisms and Helicobacter pylori

Using Probiotics as Supplementation for Helicobacter pylori Antibiotic Therapy

Probiotics in the treatment of Helicobacter pylori infection: reality and perspective

Contact Info

Product

Resources

About