Study the effectiveness of (G-6-PhD )enzyme and the level of fats in peoples with leukemia

Abstract

A chemo-enzymatic study of the enzyme G-6-PhD in the blood of people with leukemia and lipid level estimation and blood tests for cancer patients in the Kirkuk city .It included 80 samples, 30 of them are healthy as a control group and 50 patients with leukemia, which was collected from the center of cancer tumors in Kirkuk and the ages (1 to 60) years old. During this study was evaluated the level of effectiveness of G-6-PhD from red blood cells by using the diagnostic kit (BioLaBo). There is a decrease in the level of G-6-PhD enzyme effectiveness, especially in the second age group where there was a clear decrease in this category compared to healthy people. In addition, serum lipid levels were measured for people with leukemia, where they found a decrease in fat levels (HDL , CHOL) and an increase of (V.LDL , LDL ,T.G). Also, some blood tests were conducted in people with leukemia. There was a decrease in the level of (HB , PLT , PCV) and increase at the level of both (WBC) compared to healthy.

The Impact of G6PD Deficiency on Liver Function in Children Under 15

“…For the control group, 30 samples were collected from healthy people of the same age, consisting of fifteen females and fifteen males, and they were collected from external labs. The level of enzyme activity in red blood cells was estimated using the diagnostic kit supplied by (BIOLABO-France), where the principle of action depended on the estimation of the increase in the concentration of NADPH at a wavelength (340 nm), representing the activity ratio of the enzyme G6PD in the sample [12].…”