Study on the relationship between respiratory scores and hyponatremia in children with bronchiolitis

Abstract

Background: Tal et al. severity score (TSS) and Modified Wood’s Clinical Asthma Score (M-WCAS) are used to evaluate the severity of the disease in children with bronchiolitis. It has recently been suggested that there is a relationship between bronchiolitis severity and hyponatremia.
 Aims and Objective: This study aimed to evaluate the relationship between both of scores and hyponatremia in children with bronchiolitis.
 Materials and Methods: This prospective observational study included 172 patients (age range: 1-24 months) admitted to the hospital with bronchiolitis diagnosis. Demographic and clinical features of patients were recorded, and the TSS and the M-WCAS were calculated. These values and their components were compared with serum sodium (Na) results obtained at hospital admission.
 Results: Of the 172 patients, 114 (66.3%) were male, and the mean age was 5.5 ± 4.6 months. The mean TSS and M-WCAS of the patients were 6.73±1.9, and 3.34±1.4, respectively. Hyponatremia (Na<135mEq/L) was detected in 30 (17.4%) patients. When the TSS and M-WCAS of patients with and without hyponatremia were compared, there was no statistically significant difference (p = 0.517; p = 0.662, respectively); however, there was a significant relationship between hyponatremia and low oxygen saturation levels (p= 0.026).
 Conclusion: No relationship was found between hyponatremia and TSS & M-WCAS. However, the relationship between hyponatremia and hipoxia suggests that hyponatremia is likely to increase with the severity of the disease.

Incidence and Risk Factors for Hyponatremia in Hospitalized Children with Lower Respiratory Tract Infections

“…16 No relationship was found between hyponatremia and total severity score (TSS) and the modified Wood Clinical Asthma score (M-WCAS) in children with bronchiolitis in a previous study. 17 However, they found a relationship between hyponatremia and hypoxia, suggesting that hyponatremia is likely to increase with the severity of the disease. 17 Our study is the first study to show the association of serum sodium levels with severity of disease based on an objective scoring method using CRS.…”

“…17 However, they found a relationship between hyponatremia and hypoxia, suggesting that hyponatremia is likely to increase with the severity of the disease. 17 Our study is the first study to show the association of serum sodium levels with severity of disease based on an objective scoring method using CRS. An inverse correlation between severity of distress and serum sodium levels was noted in our study.…”