Study on the bacteriostatic action of Chinese herbal medicine on avian Trichosporon

Abstract

In this study, a strain of Trichosporon was isolated from white pseudomembranes and ulcers formed on mucous membranes of pigeon bursas and was identified through gene sequencing. Bacteriostatic actions of Acorus gramineus , Sophora flavescens , Polygonum hydropiper , and Chinese herbal mixture on this species were explored in vitro, and the minimum inhibitory concentration of herbal medicines against Trichosporon was determined through microdilution method. Therapeutic effects of herbal medicines on chickens infected by Trichosporon were studied, whose results showed that minimum inhibitory concentration of A. gramineus was 32 μg/μL, that of S. flavescens was 2 μg/μL, that of P. hydropiper was 120 μg/μL, and that of Chinese herbal mixture was 36 μg/μL. Antibacterial effects of S. flavescens were the best. In accordance with animal experiments, therapeutic effects of Chinese herbal medicines on infected chickens were better than those of fluconazole. The mortality rate of the Chinese herbal medicine treatment group was 33.33%, that of the fluconazole treatment group was 46.67%, and that of the Chinese medicine protection group was 23.33%. The longer the time of Chinese medicine treatments was, the better the treatment effects would be. Glutamic oxaloacetylase values of the serum and liver in the Chinese herbal medicine treatment group were both significantly lower than those of the nontreatment group. From the results, it can be seen that A. gramineus , S. flavescens , P. hydropiper , and Chinese herbal mixture have certain inhibitory effects on Trichosporon spp. Chinese herbal medicine protections in advance could reduce Trichosporon infections.

Effect of Dietary Paeoniae Radix Alba Extract on the Growth Performance, Nutrient Digestibility and Metabolism, Serum Biochemistry, and Small Intestine Histomorphology of Raccoon Dog During the Growing Period

“…4. Chinese herbal medicine can adjust the structure of intestinal flora, improve the intestinal environment of animals, promote the reproduction of beneficial bacteria, prevent intestinal villus atrophy, and promote the absorption of nutrients by intestinal mucosa ( 22 – 27 ). In this study, the addition of PRA extract did not promote the digestion of nutrients compared to group PRA0 (0 g/kg PRA extract).…”

Preventive effect of Terminalia bellirica (Gaertn.) Roxb. extract on mice infected with Salmonella Typhimurium

“…g ., improving animal growth performance, immunity, and regulating gut microbiota ( Abarike et al., 2019 ; Wang et al., 2020 ; Gao et al., 2022 ). Recent studies indicate that these inhibit the growth of Staphylococcus aureus , Salmonella cholerae suis , Escherichia coli , Streptococcus agalactiae ( Zou et al., 2022a ), Trichosporon ( Zhang et al., 2020 ), Candida glabrata ( Zhang et al., 2021 ), Aspergillus flavus , and Aspergillus fumigatus ( Xue et al., 2022 ). Meanwhile, they play a vital role in livestock and poultry farming by enhancing humoral and cellular immune responses ( Ma et al., 2013 ), nutrient digestion and absorption ( Kong et al., 2009 ), and modulating the gut microbiota composition ( Waititu et al., 2017 ).…”

Preparation and properties of nano-TiO2-Chinese herbal medicine composite wood

“…Five low-price Chinese herbal medicines were considered: Sophora flavescens, Hypericum perforatum, Cnidium monnieri, Kochia scoparia, and Zanthoxylum bungeanum. The ratio of 1:8 Chinese herbal medicine and distilled water was used, and the specimens were soaked for 30 min; then the mixture was heated and boiled (Zhang et al 2020). Then the TiO2 sol and the 0.6% Sophora flavescens water extract were added to the hydrothermal reactor at a ratio of 1:1.2, and the specimens were subjected to composite modification treatment by the hydrothermal method.…”