Study on postpartum estrus of guinea pigs (Cavia cobaya) using Anredera cordifolia leaf extract

Wijayanti, Dwi; Setiatin, Enny Tantini; Kurnianto, Edy

doi:10.14202/vetworld.2017.375-379

Cited by 7 publications

(9 citation statements)

References 20 publications

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“…According to Wijayanti et al (2018), the content of flavonoids, saponins, alkaloids and vitamin C in A. cordifolia leaves has a positive effect on kidney C. cobaya with a certain dose. Flavonoids as antioxidants can act as an antidote to free radicals (Wijayanti et al, 2017;Mushollaeni et al, 2014). Flavonoids function to protect cell membranes from oxidative stress.…”

Section: Resultsmentioning

confidence: 99%

“…Giving of A. cordifolia leaf extract of 0, 10, 50, and 90 mg /head with treatment design T0, T1, T2 and T3. Each treatment was given 2 female C. cobaya and A. cordifolia leaf extract were administered orally for 10 days prepartum (Wijayanti et al, 2017;Wijayanti et al, 2018).…”

Section: Experimental Designmentioning

confidence: 99%

“…The contents of A. cordifolia leaves were flavonoids, saponins, terpenoids, tannins, antioxidants and phytoestrogens (Miladiyah and Prabowo, 2015). According to Wijayanti et al (2017), C. cobaya given 50 mg / head of A. cordifolia leaf extract can accelerate the onset of postpartum estrus in C. cobaya after giving 10 prepartum days to 10 days after postpartum. Flavonoid content in A. cordifolia extract can improve the profile of red blood in C. cobaya (Wijayanti et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

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Toxicity Effect by Binahong (Anredera cordifolia) Leaf Extract in Histopathology and Liver Weight of Guinea Pigs (Cavia cobaya)

Wijayanti¹,

Kurnianto

Setiatin

2019

BuletinPeternak

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The aim of this research was to determine the toxic effect of Anredera cordifolia leaf extract on the Cavia cobaya liver which was evaluated by the histopathological examination of liver tissue. The materials used were 8 female guinea pigs 2.5 months old that were divided into 4 groups by simple random sampling, each treatment was given to 2 female C. cobaya. Treatments given were 0, 10, 50 and 90 mg of A. cordifolia leaf extract/head, designated as T0, T1, T2 and T3, respectively. Materials were given treatment daily as long as 10 days prepartum. All of the guinea pigs were slaughtered at day 11, and the liver were taken to examined their histopathological changes. Each of the liver tissues were processed by paraffin blockembedded and hematoxylin eosin (HE) staining method. The results of this study indicate the presence of albuminosa degeneration or mild degeneration (DH +) from group control and hydropic degeneration or moderate degeneration (DH ++) in all treatment groups and the weight of C. cobaya liver which was given an extract of A. cordifolia 50 mg/head was not significantly different from the control but was significantly different from 10 and 90 mg/head. The conclusion was Binahong's (A. cordifolia) leaves extract up to the dosage 90 mg/head had no significantly toxicity effect on the liver of guinea pigs (C. cobaya).

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Section: Resultsmentioning

confidence: 99%

Section: Experimental Designmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Toxicity Effect by Binahong (Anredera cordifolia) Leaf Extract in Histopathology and Liver Weight of Guinea Pigs (Cavia cobaya)

Wijayanti¹,

Kurnianto

Setiatin

2019

BuletinPeternak

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“…The total of flavonoid content was determined by visible spectrophotometry as described by Wijayanti et al (2017). Fresh leaves of A. cordifolia weighed 500 g then finely ground to maceration with ethanol (1:10) at room temperature for 5 days (Wijayanti et al, 2017).…”

Section: Determination Of Total Flavonoid and Amentioning

confidence: 99%

Leucocyte profile and offspring production of guinea pig (Cavia cobaya) given Anredera cordifolia leaf extract

Wijayanti¹,

Setiatin

Kurnianto

2018

J. Indonesian Trop. Anim. Agric.

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ABSTRAKTujuan penelitian ini adalah mengetahui profil leukosit dan jumlah anak dari marmut (Cavia cobaya) akibat pemberian ekstrak daun binahong (Anredera cordifolia). Materi yang digunakan adalah marmut betina masing-masing berjumlah 16 ekor dengan bobot badan 425 g. Ekstrak daun binahong dengan dosis 0, 10, 50 dan 90 mg, masing-masing ditetapkan sebagai T0, T1, T2 dan T3. Pemberian dilakukan secara oral, dari 0 hari prepartum sampai 10 hari postpartum. Pengambilan darah dilakukan 10 hari prepartum, pasca beranak, 10 hari postpartum, dan juga dilakukan pengamatan jumlah kelahiran dan kematian fetus pasca beranak. Data dianalisis menggunakan analisis ragam dilanjut analisis beda ratarata dengan Duncan Multiple Range Test untuk tampilan leukosit dan Chi-Square untuk produksi anak yang diberi ekstrak daun A. cordifolia dengan kontrol. Hasil menunjukkan bahwa kelompok perlakuan 10 hari prepartum (control) tidak berbeda nyata, kelompok perlakuan postpartum pada monosit total terjadi kenaikan tertinggi pada level 50 mg/ekor dibandingkan dengan level 0, 10, dan 90 mg/ekor. Kelompok perlakuan 10 hari postpartum pada leukosit total dan monosit total terjadi kenaikan tertinggi pada level 50 dan 90 mg/ekor dibandingkan 10 mg/ekor. Limfosit total terjadi kenaikan tertinggi pada level 90 mg/ekor dibandingkan dengan level 10 dan 50 mg/ekor. Neutrofil total kenaikan tertinggi pada level 50 mg/ekor dibandingkan dengan level 0 dan 10 mg/ekor. Pemberian ekstrak daun A. cordifolia dapat menaikan jumlah anak yang dilahirkan (P<0,05; χ2=9,267) dan dapat menurunkan jumlah anak yang mati (P<0,05; χ2=6,4). Kesimpulannya adalah pemberian ekstrak daun A. cordifolia 50 mg/ekor dapat meningkatkan profil leukosit dan produksi keturunan.Kata kunci: Anredera cordifolia, total leukosit, differensial leukosit, Cavia cobaya, produksi keturunan ABSTRACTThe objective of this study was to determine leucocyte and offspring production of guinea pig (Cavia cobaya) giving Anredera cordifolia leaf extract. Materials used were female 16 heads of guinea pig with body weight of 425g. The treatments were an extract of A. cordifolia leaf at doses of 0, 10, 50 and 90 mg/head, designated as T0, T1, T2 and T3, respectively. A. cordifolia leaf extract was administered orally from 10 days prepartum to 10 days postpartum. Blood was taken at 10 days prepartum and 10 days postpartum. Total birth of the offspring was observed. Data were analyzed by analysis of variance and if there was effect of treatment, then continued with Duncan multiple range test and Chi-Square test for fetal production between the given A. cordifolia leaf extract and control. The result showed that there was no significant difference for 10 days prepartum after addition of A. Leucocyte Profile in Guinea Pig Given Anredera Cordifolia (D. Wijayanti et al.) 19 cordifolia leaf extract treatment. The postpartum treated showed a total 50 mg/head level increaed for monocytes than that of level 0, 10 and 90 mg/head. Ten days postpartum treatment showed the total increase for leucocyte and monocyte...

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“…Tanaman Binahong adalah salah satu tanaman herbal yang memiliki khasiat sebagai anti mikroba, antibakteri dan antibody. Kandungan didalam daun Binahong seperti flavonoid, saponin, tannin, terpenoid dan alkaloid yang memiliki aktivitas antibakteri tinggi [8].…”

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Pengembangan Larutan Daun Binahong Sebagai Antiseptic Mengatasi Mastitis Pada Sapi Perah Di Kelompok Ternak Giri Mukti, Tasikmalaya

Wijayanti¹,

Ardigurnita²

2019

j-dinamika

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AbstrakTujuan dari pengabdian masyarakat ini adalah untuk menjadikan kelompok ternak Giri Mukti di desa Guranteng kecamatan Pageurageung kabupaten Tasikmalaya menjadi kelompok ternak dengan tingkat produktivitas dan reproduksi yang tinggi dengan penurunan penyakit mastitis. Tujuan khusus dari setiap rencana tahun pengabdian masyarakat adalah pengenalan, pengecekan status reproduksi dan pembuatan larutan daun Binahong sebagai antibakteri (mastitis). Metode yang digunakan adalah survey, transfer teknologi dan plot demonstrasi. Kegiatan ini diharapkan dapat menjadi salah satu alternative dalam penanggulangan, pencegahan gangguan reproduksi dan kesehatan khususnya mastitis dengan penggunaan tanaman herbal yaitu daun binahong. Permasalahan turunnya produksi susu, penyakit mastitis dan kurangnya perhatian peternak terhadap perkembangan sapi teratasi dengan obat antiseptic yang berasal dari daun binahong.Kata Kunci -Daun Binahong, Mastitis, Teat Dipping dan Sapi Perah.

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Study on postpartum estrus of guinea pigs (Cavia cobaya) using Anredera cordifolia leaf extract

Cited by 7 publications

References 20 publications

Toxicity Effect by Binahong (Anredera cordifolia) Leaf Extract in Histopathology and Liver Weight of Guinea Pigs (Cavia cobaya)

Toxicity Effect by Binahong (Anredera cordifolia) Leaf Extract in Histopathology and Liver Weight of Guinea Pigs (Cavia cobaya)

Leucocyte profile and offspring production of guinea pig (Cavia cobaya) given Anredera cordifolia leaf extract

Pengembangan Larutan Daun Binahong Sebagai Antiseptic Mengatasi Mastitis Pada Sapi Perah Di Kelompok Ternak Giri Mukti, Tasikmalaya

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