Study on Conventional Risk Factors in Acute Coronary  Syndrome

Khatri, Prabin; Simkhada, Rabindra

doi:10.3126/jucms.v3i2.14282

Cited by 9 publications

(11 citation statements)

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“…In this study, the most common risk factor for ACS was hypertension (46.4%). Similar finding was claimed by other studies too; hypertension was the most frequent risk factor in India (48.4%) [22], Nepal (68%) [23], Greece (58.8%) [24]and Senegal (46%) [25]. Plausible explanation could be due to hypertensive patients might have poor knowledge and attitude on the prevention of cardiovascular complications; such as adhering life style adjustment, having appropriate follow up and adhering to their medications accordingly [26].…”

Section: Discussionsupporting

confidence: 76%

Treatment outcome of acute coronary syndrome patients admitted to Ayder Comprehensive Specialized Hospital, Mekelle, Ethiopia; A retrospective cross-sectional study

et al. 2020

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Background Acute coronary syndrome (ACS) is increasingly becoming a common cause of cardiovascular mortality in developing countries. Even though, there is an introduction of limited percutaneous coronary intervention and thrombolytic therapies, in-hospital mortality due to ACS still remains high in sub-Saharan countries. Objective The aim of the study was to assess treatment outcome of ACS patients admitted to Ayder Comprehensive Specialized Hospital, Mekelle, Ethiopia. Methods A retrospective cross-sectional study was done by collecting data from patients' medical records using a data abstraction tool. Data were analyzed using logistic regression to determine crude and adjusted odds ratio. At 95% confidence interval, p-value<0.05 was considered as statistically significant. Results Of the total 151 patients, in-hospital mortality was found to be 24.5%, and hypertension was the most frequent (46.4%) risk factor of ACS. Concerning the management practice, catheterization and primary percutaneous coronary intervention were done in 27.1%, and 3.9% respectively. Additionally, in emergency setting loading dose of aspirin and clopidogrel were used in about 63.8% and 62.8%, respectively. The other frequently used medications were beta-blockers (86.9%), angiotensin converting enzymes/angiotensin receptor blockers

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Section: Discussionsupporting

confidence: 76%

Treatment outcome of acute coronary syndrome patients admitted to Ayder Comprehensive Specialized Hospital, Mekelle, Ethiopia; A retrospective cross-sectional study

et al. 2020

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“…In the present study, results show half number 42 (51.2%) were hypertensive and 40 (48.8%) were non-hypertensive, 36 (43.9%) were diabetic and 46(56.1%) were non-diabetic which is in agreement with study done by Sinan Deveci et al [11] which shows 703 (69%) were hypertensive, 292 (28.9%) were diabetic. Similarly, in the study done by Khatri et al [11] where 68 (68%) were hypertensive and 32 (32%) were non-hypertensive, 19 (19%) were diabetic and maximum were nondiabetic i.e. 81 (81%).…”

Section: Discussionsupporting

confidence: 92%

“…Among the total study population, 36 (43.9%) had STEMI, 29 (35.4%) had NSTEMI and 17 (20.7%) had UA which shows maximum population have MI and least has UA which in agreement with study conducted by Paudel et al where 122 patients (49.6%) had STEMI but in contrast to the same study 26 (10.6%) had NSTEMI and 98 (39.8%) had UA [10]. Likewise, it is in agreement with study done by Khatri et al which also shows majority 44 (44%) of study population had STEMI [11].…”

Section: Discussionsupporting

confidence: 88%

Study of Serum Uric Acid Level in Acute Coronary Syndrome

Karki¹,

Rokaya²,

Khatri³

et al. 2019

TJSR

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At present, cardiovascular diseases are global health problems responsible for 17.3 million deaths per year and adding extra burden in developing countries like Nepal. Studies show that serum uric acid (SUA) can result in endothelial dysfunction which can lead to vascular disease like stroke. In this study, we determined serum uric acid levels in patients with acute coronary syndrome (ACS) and assess its risk factors. A cross sectional study was conducted in 82 patients with ACS who fulfilled the inclusion criteria included in the study and their serum uric acid level were investigated. It was found that 51 (62.2%) were males and 31 (37.8%) were females. Mean age in study population was 60.26 ± 11.34 years. Majority of the population belongs to 56-65 years age group. The mean uric acid level of our study population was 6.03 ± 1.50 mg/dl (male = 5.92 ± 1.72, female = 6.64 ± 1.53). SUA ≥ 7 mg/dl was maximum in 56-65 years age group and there was no association between age and SUA (P value = 0.146). Over half of the study population were hypertensive i.e. 42 (51.21%) and smoker i.e. 43 (52.43%). It showed association between SUA and ACS (P value = 0.003). Among those having diabetes, maximum have SUA ≥ 7 mg/dl i.e. 17 (47.22%). Among those having high cholesterol level, male have higher incidence than female with no association between T. Cholesterol and gender (P value = 0.49). The mean value of T. Cholesterol was 189.83 ± 46.81 mg/dl (male = 198.78 ± 55.19 mg/dl, female = 202.30 ± 54.92 mg/dl) with (P value = 0.52). In conclusion, the mean age of ACS patients was 60.26 years, with the peak incidence at the age of 56-65 years. The ACS had male predominance. The potential risk factors of ACS were: Age >56 years (65.83%), male sex (62.2%), dyslipidemia (35.36%, hypertension (51.2%), diabetes mellitus (43.9%), smoking (52.4%) and alcohol consumption (39%). Among these SUA significantly associated with risk factors were-Sex, Diabetes Mellitus, T. Cholesterol. There was association between serum uric acid level and ACS patients. Hypertension and smoking constitutes one of the major risk factor for ACS in study population.

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“…22 Similar type high prevalence is also evident among the patients with acute coronary syndrome in Nepal. 23 Less proficient in knowledge about CVD and a poor understanding of diet and exercise in reducing CVD & the association of tobacco smoking with CVD mortality was among the Bangladeshi population by a survey in Dhaka city specially in poor, uneducated population from low socioeconomic condition. 24 This is probably also applicable in this population in the suburb near Dhaka city is the reason high prevalence of cardiovascular risk factors.…”

Section: Discussionmentioning

confidence: 99%

Cardiovascular Risk Factors in Patients with Acute MI in a Secondary Hospital in Bangladesh

Ullah

Saha

Rahman³

et al. 2020

Cardiovasc. j.

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Background: Incidence of noncommunicable disease, specially cardiovascular diseases, is increasing in Bangladesh. Prevalence of risk factors in ischaemic heart disease (IHD) has been studied in different tertiary hospitals and institutes. This study was done in a secondary hospital with a patient population mainly of low socioeconomic condition and was compared with other patient groups of the country and Indian subcontinent. Methods: this cross sectional study was conducted in Manikganj Sadar Hospital from July 2019 to December 2019. All the patients admitted with the diagnosis of myocardial infarction (MI) were included. Cardiovascular risk factors, like smoking, diabetes mellitus (DM), hypertension (HTN), family history of premature cardiovascular diseases, dyslipidaemia and obesity, were evaluated among the patients. Results: This cross-sectional study showed most of the patients were in the age group of 50-59 years. 66% of the male patients and 2% of the female patients were smoker. 66% of the patients were hypertensive, 44% patients were diabetic, 28.5% patients were overweight, 60.4% patients had total cholesterol > 200mg/dl, 73.6% patients had LDL>130 mg/dl, 110 76.3% patients had HDL < 40 mg/ dl, 72.2% had triglyceride >150 mg/dl and 39% patients had family history of premature cardiovascular disease. Ninety (62.5%) patients had anterior MI, 50 (34.7%) patients had inferior MI and 4 (2.7%) patients had NSTEMI. 65 patients had no major risk factor and 57 % had three or more risk factors. Conclusion: The study population was more aged in comparison to other studies conducted in different parts of Bangladesh. Prevalence of smoking habit was lower but the prevalence of HTN, DM and dyslipidaemia were higher than the general population and other cohorts of MI patients. The prevalence of major risk factors was much higher than the general population of Bangladesh. Cardiovasc. j. 2020; 12(2): 96-101

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Study on Conventional Risk Factors in Acute Coronary Syndrome

Cited by 9 publications

References 0 publications

Treatment outcome of acute coronary syndrome patients admitted to Ayder Comprehensive Specialized Hospital, Mekelle, Ethiopia; A retrospective cross-sectional study

Treatment outcome of acute coronary syndrome patients admitted to Ayder Comprehensive Specialized Hospital, Mekelle, Ethiopia; A retrospective cross-sectional study

Study of Serum Uric Acid Level in Acute Coronary Syndrome

Cardiovascular Risk Factors in Patients with Acute MI in a Secondary Hospital in Bangladesh

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