Study on acute toxicity of compound coggygria oral liquid

Wen, Zhaowei; Sun, Jianhua; Hao, Shaojun; Xie, Guofeng; Li, Xianyu; Zhang, Zhengchen

doi:10.1063/1.5034290

Cited by 1 publication

(1 citation statement)

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“…It improved as well markers of oxidative stress, and inhibited NF-kB (Matić et al, 2011). The hepatoprotective effect of smoketree is currently used clinically as part of a compound formula used orally in Traditional Chinese Medicine, where it is mixed with other plant extracts obtained from Schisandra chinesis, Chuipencao (Sedum sarmentosum), wolfberry (Lycium chinense), jujube (Ziziphus jujuba), gardenia (Gardenia jasminoides) (Hao et al, 2018;Su et al, 2018). Pavlov et al (2013b) investigated the toxicity of the aqueous infusion prepared from leaves (1, 2, 4%), administered intragastrically for 30 days in a concentration of 10 ml/kg.…”

Section: Hepatic Disordersmentioning

confidence: 99%

Integrating Ethnobotany, Phytochemistry, and Pharmacology of Cotinus coggygria and Toxicodendron vernicifluum: What Predictions can be Made for the European Smoketree?

et al. 2021

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The smoketree (Cotinus coggygria) is a historically known medicinal plant from Southeast Europe. Its ethnomedicinal use in skin and mucosal lesions is commonly accepted across countries. Other utilizations reported locally include fever reduction, cardiac diseases, hypertension, urinary diseases, cough, asthma, hemorrhoids, diabetes, numbness of arm, liver disease, and cancer. Departing from the smoketree’s traditional uses, this review summarizes investigations on the phytochemistry and bioactivity of the plant. In vitro and in vivo experiments supporting wound-healing, anti-inflammatory, antibacterial, cytotoxic, antioxidative, hepatoprotective, and antidiabetic effects are presented. Metabolites from smoketree that are responsible for the main pharmacological effects of smoketree are pointed out. Furthermore, the review performs a comparison between C. coggygria and the lacquer tree (Toxicodendron vernicifluum). The latter is a comprehensively studied species used in Asian phytotherapy, with whom the European smoketree shares a consistent pool of secondary metabolites. The comparative approach aims to open new perspectives in the research of smoketree and anticipates an optimized use of C. coggygria in therapy. It also points out the relevance of a chemosystematic approach in the field of medicinal plants research.

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Section: Hepatic Disordersmentioning

confidence: 99%