Study of the reaction between genipin and amino acids, dairy proteins, and milk to form a blue colorant ingredient

Synergic effect of natural deep eutectic solvent and high-intensity ultrasound on obtaining a ready-to-use genipin extract: Crosslinking and anti-neurodegenerative properties

“…In the presence of oxygen, genipin can spontaneously react with primary amines of amino acids, peptides, proteins, or other polymers which contain amine groups through a crosslinking process used for some technological applications ( Neri-Numa et al, 2020 ). This reaction produces a blue pigment with a maximum absorbance at 590 nm ( Neves, Valdés, Silva, Meireles, Ibañéz, Cifuentes, 2022 ). Fig.…”

“…The crosslinking reaction between genipin and primary amines from amino acids, proteins or polymers produces a blue pigment ( Neves, Valdés, Silva, Meireles, Ibañéz, Cifuentes, 2022 ). The effect of NADES on the genipin crosslinking capacity was evaluated by determining the absorption modification of the solutions at 590 nm (wavelength corresponding to the blue).…”

New sources of genipin-rich substances for crosslinking future manufactured bio-based materials

“…Thus, it is an important reagent to produce future bio-based materials approved for human contact. [14][15][16][17][18][19] Genipin is an iridoid, a secondary plant metabolite that is part of the monoterpenoids and has hydroxyl groups in its structure that give it a polar character. Genipin can also form covalent bonds with amino groups, forming polysaccharide or protein crosslinking networks.…”

Study of Genipin Behavior in Neutral and Acidic Aqueous Solutions at Elevated Temperatures

“…In 1987, genipin was observed to undergo a quick reaction with the simplest amino acid, glycine [6] . Later on, genipin has been commonly used to react with other amino acids, [7] and more complex amine‐containing structures such as chitosan, [8,9] collagen, [10] gelatin, [11] and enzymes [12] . Similar to other bifunctional crosslinkers, genipin can act as a “staple” of amine‐containing polymers to finally give stable crosslinked matrixes (Figure 1).…”