Synergic effect of natural deep eutectic solvent and high-intensity ultrasound on obtaining a ready-to-use genipin extract: Crosslinking and anti-neurodegenerative properties

Neves, Maria Isabel Landim; Socas‐Rodríguez, Bárbara; Valdés, Alberto; Silva, Eric Keven; Cifuentes, Alejandro; Meireles, M. Angela A.; Ibáñez, Elena

doi:10.1016/j.fochx.2022.100489

Cited by 5 publications

(1 citation statement)

References 43 publications

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“… ipecacuanha, poaia 104 Not mentioned Native Emetic, expectorant, diaphoretic (sudorific) Expectorant † [ 131 ], emetic † [ 132 , 133 ], immunomodulatory [ 134 ] Genipa americana L. (= Genipa brasiliensis (Sprend.) Baill) jenipapo 106 Fruit Native Medicinal (undefined) Antiplatelet, anti-inflammatory [ 135 ]; neuroprotective [ 136 ]; antioxidant, anti-glycant [ 137 ]; antithrombotic [ 138 ]; anticonvulsant [ 139 ]; trypanocidal [ 140 ] Sapindaceae Paullinia cupana Kunth. (= Paullinia sorbilis Mart.)…”

Section: Resultsmentioning

confidence: 99%

Amazonian useful plants described in the book “Le Pays des Amazones” (1885) of the Brazilian propagandist Baron de Santa-Anna Nery: a historical and ethnobotanical perspective

Silva,

Oliveira,

Baratto

2024

J Ethnobiology Ethnomedicine

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Background Frederico José de Santa-Anna Nery (1848–1901) was a Brazilian Baron who referred to himself as a "volunteer propagandist" for Brazil in Europe, serving as an immigration agent to publicize the living conditions in the Amazon region, advocating for its development and modernization at the end of the nineteenth century. Santa-Anna Nery’s most famous book is "Le Pays des Amazones" (The Lands of the Amazons), first published in 1885, which the author dedicated a chapter to introduce and report on the Amazonian useful plant species and its relationship with humans. The aim of this work is to understand the historical context and ethnobotanical value of the plant species in the Brazilian Amazon at the end of the nineteenth century through an analysis of the book “Le Pays des Amazones” (1885) by Baron de Santa-Anna Nery, as well as to bring to light the historical importance of this very influential propagandist, who has been forgotten nowadays. Methods The original book “Le Pays des Amazones” (1885), as well as the original 3rd edition and its translated version into Portuguese, was carefully analyzed and all information about plants was systematized, with botanical names being updated. Finally, using the scientific name of medicinal plants alone or in combination with their traditional use, a search was carried out in databases in order to indicate current pharmacological studies that provide evidence about the described traditional uses. Results A total of 156 plant species were identified in the book, although 132 species had their scientific names updated. These species belong to 45 different families, with Fabaceae and Arecaceae the most represented, and 109 plants are Brazilian native. Considering only the 36 medicinal plants, the main medicinal indications reported were astringent, purgative/laxative, stimulant and tonic, vermifuge, febrifuge, sudorific, emetic, diuretic and antidysenteric. Regarding other useful plants (non-medicinal), 97 species were cited for food, constructions and buildings, spices and condiments, ornaments and objects, carpentry, textile fibers, gums, oils, balms and essences, pigments and tanning, hunting and fishing. Conclusions When the book “Le Pays des Amazones” is analyzed from a timeless perspective, with a particular focus on historical ethnobotany, it is possible to observe the economic, social, and political importance of many useful plants for the Amazon at the end of the nineteenth century and how the relationship between local people, indigenous communities, and immigrants was established with plant biodiversity.

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Section: Resultsmentioning

confidence: 99%

Amazonian useful plants described in the book “Le Pays des Amazones” (1885) of the Brazilian propagandist Baron de Santa-Anna Nery: a historical and ethnobotanical perspective

Silva,

Oliveira,

Baratto

2024

J Ethnobiology Ethnomedicine

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A comprehensive review on genipin: an efficient natural cross-linker for biopolymers

Wahba

2024

Polym. Bull.

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Cross-linkers are pivotal to meliorate the attributes of the biopolymers, which are exploited in the biomedical industries, and also those intended as packaging supplies. Genipin (GN) is an efficacious cross-linker. Moreover, being naturally procured, biodegradable and biocompatible makes it an auspicious candidate for the biomedical and food industries. Accordingly, we attempted to provide a comprehensive review on GN as an efficient cross-linker for biopolymers. Initially, we presented the chief botanical sources of GN. The GN extraction strategies, which adopted safe solvents, were then discussed while highlighting their realized yields. The proposed GN structures, its possible modes of action, and the factors affecting its interactions, such as pH, temperature, and GN concentration were also reviewed. Afterward, the GN applications that mainly involved cross-linking biopolymers and biopolymers containing materials were discussed. These included tissue engineering, wound dressings, drug delivery, and packaging applications. GN capability to activate biopolymers, such as chitosan and gelatin, into covalently reactive enzyme immobilizers was also discussed. Moreover, other important GN applications, such as exploiting it as a colorant for foods and textiles and incorporating it in altered biosensors, were discussed.

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Genipin’s potential as an anti-cancer agent: from phytochemical origins to clinical prospects

Natallia,

Dama,

Gorica

et al. 2024

Med Oncol

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Synergic effect of natural deep eutectic solvent and high-intensity ultrasound on obtaining a ready-to-use genipin extract: Crosslinking and anti-neurodegenerative properties

Cited by 5 publications

References 43 publications

Amazonian useful plants described in the book “Le Pays des Amazones” (1885) of the Brazilian propagandist Baron de Santa-Anna Nery: a historical and ethnobotanical perspective

Amazonian useful plants described in the book “Le Pays des Amazones” (1885) of the Brazilian propagandist Baron de Santa-Anna Nery: a historical and ethnobotanical perspective

A comprehensive review on genipin: an efficient natural cross-linker for biopolymers

Genipin’s potential as an anti-cancer agent: from phytochemical origins to clinical prospects

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