Study of the prevalence and patterns of phosphodiesterase type 5 inhibitor use among sexually active Egyptian males: A National Cross‐sectional Survey

Attia, Attia Abd‐Allah; Abdel-Hameed, Ahmad Kamel Seddeik; Amer, Mohamed; Malekinejad, Hassan; Din, Sameh Fayek GamalEl; El‐Moslemany, Hossam El‐Din Gaber Mohamed

doi:10.1111/and.13364

Cited by 10 publications

(9 citation statements)

References 16 publications

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“…It is usual that studies addressing sexual function conducted on Egyptian males encounter similar rejection to complete the questionnaires and refusal to openly discuss sexual complaints with the medical personnel. 29,30 In conservative eastern countries, males with sexual dysfunction or a recognizable sexual problem are considered deficient by their partners and acquaintances. Male sexual function is perceived to be equivalent to masculinity and any declared dissatisfaction is believed to threaten this masculine genital pride and male dominance.…”

Section: Discussionmentioning

confidence: 99%

Psychological and Sexual Health During the COVID-19 Pandemic in Egypt: Are Women Suffering More?

et al. 2021

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Introduction: Psychological consequences of the COVID-19 pandemic include pandemic triggered feelings of fear, uncertainty, and anxiety added to the effects of restricting the population's activities in lockdown. Aim: We aimed to study the effect of COVID-19 pandemic on sexual satisfaction of females and males in Egypt and to evaluate possible predictive factors. Methods: Married men and females in Egypt were invited to respond to an online questionnaire. The questionnaire addressed medical history, socioeconomic status, sexual performance satisfaction before and during the lockdown in addition to validated Arabic questionnaires for depression, sexual function in males and females, and sexual satisfaction (Generalized Anxiety Disorder-7, Patient Health Questionnaire-9, Female Sexual Function Index, International Index of Erectile Function-5, Index of Sexual Satisfaction, respectively). Main outcome measure: The main outcome measures were frequency of depression, anxiety, sexual dysfunction, and sexual satisfaction in males and females during COVID-19 lockdown. Results: A total of 479 females and 217 males completed the questionnaire. Sexual satisfaction was significantly higher before (91.2%, 73.5%) than during lockdown (70.5%, 56.2%) in both males and females, respectively. During lockdown, significantly more males (70.5%) reported being satisfied with their sexual performance than females (56.2%) (P < .001). More than half of the male subjects (68.2%) had no erectile dysfunction while 97.3% females scored 26.5 on the Female Sexual Function Index scale suggestive of sexual difficulties. Sexual stress was significantly greater in females (70.8%) than males (63.1%). Educational level, occupation, anxiety, and erectile dysfunction were independently associated with sexual stress in males. Being a housewife or unemployed, husband's age >35 years, marriage duration of 5-10 years, anxiety, and female sexual dysfunction were predictors of sexual relation stress in females. Conclusion: COVID-19 pandemic was associated with lower sexual satisfaction in both genders. Females however suffered more anxiety and depression and thereby greater risk of sexual function difficulties and sexual dissatisfaction. Intervention strategies in order to lessen the suffering of affected individuals particularly after the pandemic are recommended.

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Section: Discussionmentioning

confidence: 99%

Psychological and Sexual Health During the COVID-19 Pandemic in Egypt: Are Women Suffering More?

et al. 2021

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“…Similarly, the users of the sex-enhancing medications had several sexual characteristics, including longer duration and higher frequency of sexual activity, but lower level of sexual satisfaction [7] . Moreover, a significantly higher percentage of extramarital sexual activity among sex-enhancing medications users than the nonusers was reported [22] .…”

Section: Resultsmentioning

confidence: 96%

“…The low rate of consultation before using sex-enhancing medications could be explained by the embarrassment. Meanwhile, the lack of definite regulations governing the purchasing of such medications without consultation may have increased the rate of misusing these drugs [22] .…”

Section: Resultsmentioning

confidence: 99%

Users under the influence of sex-enhancing medications: prevalence, demographics, and sexual features

Aboraia

Raheem²,

ELSAWAH³

et al. 2022

Human Andrology

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Background: Erectile dysfunction (ED) is considered the prime sexual dysfunction attracting public attention among men all over the world. It ranges from partial decrease in penile rigidity to a complete erectile failure. To overcome this issue, sexenhancing medications have become popular among men. Aim: The main objective of this work was to determine the prevalence, demographics, and sexual features of sex-enhancing medications users among Egyptians. Patients and Methods: A total of 1916 adult males were included in the present study. This cross-sectional study was conducted between August 2020 and July 2021. Participants were invited to fill a self-structured questionnaire through 'Google Forms.' The form included three main sections for sociodemographic data; sexual activity, and sex-enhancing medication history and brief sexual functioning inventory score analysis (BSFI). Results: Our finding showed that 48.4% of the subjects used sex-enhancement drugs. After completing the BSFI score variables, the results revealed that there was a highly statistically significant difference for the total BSFI score between sexenhancement drug users and nonusers (23.4±5.7 and 21.02±4.5, respectively), with less than 0.001. Regarding the drugs used, the majority (67.9%) used sildenafil. Strengths and limitations: In the Egyptian society, talking about sex problems concerns most males and they get ashamed when talking about it. Sex-enhancement drugs are being circulated in Egypt in a nonmedical way. Conclusion: Urban residency, marriage, high education, job, low-to-middle socioeconomic status, smoking, drinking alcohol, and having chronic hypertension and/or diabetes mellitus were identified as features of sex-enhancing pharmaceutical users, with impairment of sexual function among them.

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“…Despite being a not life-threatening condition, the associated stigma of ED causes men and their partners to suffer in silence [6]. Inhibitors of phosphodiesterase type 5 (PDE5-Is), including tadalafil, are the first-line ED-treating drugs [7].…”

Section: Introductionmentioning

confidence: 99%

Effect of Adding a 2-Month Consequent Continuous and Interval Elliptical Aerobic Training to Once-Daily 5-mg Tadalafil Administration on Erectile Dysfunction in Obese Men

Ismail

Abdelghany

2022

Sex Disabil

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Exercise (Ex) shares the first-line approach with pharmacological inhibitors of phosphodiesterase type 5 (PDE5-Is), including tadalafil, in the treatment of erectile dysfunction (ED) in obese men. The effect of elliptical training (ET) on ED was not questioned in the literature. This study aimed to clarify the effect of adding a 2-month consequent continuous and interval ET to once-daily 5-mg tadalafil administration on ED in obese men. Sixty obese men aged 34-56 years with ED were randomly assigned to the Ex group (n = 30) and the non-Ex group (n = 30). Both groups received 8-week oral tadalafil administration (five-milligram tablet, one time/day). Ex group only received a 1-h concurrent interval and continuous ET (three times/week for 2 months). Homeostasis model assessment of insulin resistance (HOMA-IR), insulin, body mass index (BMI), the circumference of the waist (WC), systolic blood pressure (SBP), high-density lipoprotein (HDL), diastolic blood pressure (DBP), triglycerides (TG), Five-Item Version of International Index of Erectile Dysfunction (IIEF-5), and fasting blood glucose (FBG) were screened before and after the trial. A significant statistical difference of all measures was ascertained from the within-Ex-group comparison (P < 0.05) while this significance was not achieved from the withincomparison of the non-Ex group (except IIEF-5 which showed a significant difference, P < 0.05). The established post-intervention comparison between Ex and non-Ex groups exhibited a non-significant difference in BMI, HDL, and WC while other variables exhibited a statistically-significant difference in favor of the Ex group. Adding 1-h consequent continuous and interval ET to tadalafil drug is a highly efficient procedure in improving ED than tadalafil alone in obese men. KeywordsExercise • Elliptical training • Interval training • Continuous training • PDE5-is • Tadalafil • Erectile dysfunction • Obesity • Egypt P.T.REC/012/002918 was the prior-documented approval number obtained from the Physical Therapy Faculty, Cairo University, after the agreement of its local ethical scientific board to conduct the trial protocol. Also, NCT04623840 was the public registered number obtained after the process of protocol registration on https://clinicaltrials.gov/.

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Study of the prevalence and patterns of phosphodiesterase type 5 inhibitor use among sexually active Egyptian males: A National Cross‐sectional Survey

Cited by 10 publications

References 16 publications

Psychological and Sexual Health During the COVID-19 Pandemic in Egypt: Are Women Suffering More?

Psychological and Sexual Health During the COVID-19 Pandemic in Egypt: Are Women Suffering More?

Users under the influence of sex-enhancing medications: prevalence, demographics, and sexual features

Effect of Adding a 2-Month Consequent Continuous and Interval Elliptical Aerobic Training to Once-Daily 5-mg Tadalafil Administration on Erectile Dysfunction in Obese Men

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