Study of the Normal Database That Affects 3D-SSP Z-score Mapping

Yamämoto, Yasushi; Haramoto, Masuo; Komatsu, Akio; Uchida, Kouji

doi:10.6009/jjrt.kj00000922345

Cited by 3 publications

(1 citation statement)

References 2 publications

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“…First, no attempt was made to examine the optional cut-off frequency of the Butterworth filter to diagnose AD. The diagnostic performance of AD might be improved if a lower cut-off frequency was used [36]. Second, the number of subjects of this study was limited, and some may consider that the NCs used in this study for configuring the NDB were limited.…”

Section: Discussionmentioning

confidence: 97%

Diagnostic performance of Tc-99m HMPAO SPECT for early and late onset Alzheimer’s disease: a clinical evaluation of linearization correction

et al. 2009

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Section: Discussionmentioning

confidence: 97%

Diagnostic performance of Tc-99m HMPAO SPECT for early and late onset Alzheimer’s disease: a clinical evaluation of linearization correction

et al. 2009

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Effects of Transmission Scan Protocol and Attenuation Correction Method on Normal Database of 2-[18F]fluoro-2-deoxy-D-glucose (18F-FDG) Brain Positron Emission Tomography Study

Kobayashi

Sugimoto²,

Maruyama³

et al. 2010

Nippon Hoshasen Gijutsu Gakkai Zasshi

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Although post-injection transmission scan (POST-TS) after 2-[(18)F]fluoro-2-deoxy- D-glucose ((18)F-FDG) injection[A1] is useful for short examination times, the emission count of (18)F-FDG[A2] in the regional brain area was not completely subtracted with use of the POST-TS method. The purpose of this study was to investigate the effect of POST-TS and attenuation correction (AC) methods on the normal database (NDB). A 10 min pre-injection transmission scan (PRE-TS) was performed before (18)F-FDG[A3] was injected in eighteen normal volunteers. A 10 min POST-TS was then conducted beginning 40 min after (18)F-FDG[A4] injection, followed by a 10 min 2-dimentional emission scanning. To reconstruct each image of normal volunteers, the reconstruction was performed using the filtered back-projection (FBP) method and the ordered subsets expectation maximization (OSEM) method, with transmission-based measured attenuation correction (MAC) and the segmented attenuation correction (SAC) technique. Subtraction images of NDB with PRE-TS or POST-TS were evaluated using 3D-SSP. A phantom study was also performed in addition to a human study, and assessment was by region of interests and profile curves. NDB images with POST-TS were significantly lower in the bilateral frontal lobes and higher in the parietal lobes and occipital lobes, including the precuneus, than those with PRE-TS, regardless of the different AC and reconstruction algorithms. Therefore, we have to be careful to confirm not only emission scan methods and reconstruction algorithms, but also TS methods and AC methods in the NDB. It will be best to perform PET examinations using the same TS methods and AC methods between NDB and patients.

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Evaluation of Several Commercial Attenuation Correction Software Programs Installed by Vendors for Data Processing: A Simulation Phantom Study

Matsutomo

Onishi

Nagaki

2011

Nippon Hoshasen Gijutsu Gakkai Zasshi

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SummaryPurpose: An attenuation correction is necessary to improve quantitative SPECT evaluation. The aim of this study was to evaluate the performance of several different types of commercial attenuation correction algorithms. Methods: We investigated the performance of four attenuation correction algorithms using a simulation phantom with and without scatter. The attenuation correction was performed on clinical SPECT workstations: GMS5500/PI (Toshiba), GMS7700/A (Toshiba), e.soft (Siemens), and Xeleris (GE). Then, the effect of the attenuation correction was evaluated using the count profile curve and attenuation coefficient that maintained uniformity of the radioisotope distribution in the uniform region of the images. Results: In the without-scatter condition, the count profile curve showed a similar shape on all workstations. The attenuation coefficients that maintained uniformity were 0.134, 0.133, 0.133, and 0.135 cm -1 using GMS5500/PI, GMS7700/A, e.soft, and Xeleris, respectively. There was no significant difference among these workstations. With scatter, the attenuation coefficients differed by 0.109-0.121 cm -1 with the types of attenuation correction algorithms. Conclusion: Without scatter, the effects of the attenuation corrections were equivalent. However, with scatter, a few differences were observed in the effects of correction with several types of algorithms. Therefore, our results suggest that careful evaluation should be considered when different types of clinical SPECT workstations are used.

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Study of the Normal Database That Affects 3D-SSP Z-score Mapping

Cited by 3 publications

References 2 publications

Diagnostic performance of Tc-99m HMPAO SPECT for early and late onset Alzheimer’s disease: a clinical evaluation of linearization correction

Diagnostic performance of Tc-99m HMPAO SPECT for early and late onset Alzheimer’s disease: a clinical evaluation of linearization correction

Effects of Transmission Scan Protocol and Attenuation Correction Method on Normal Database of 2-[18F]fluoro-2-deoxy-D-glucose (18F-FDG) Brain Positron Emission Tomography Study

Evaluation of Several Commercial Attenuation Correction Software Programs Installed by Vendors for Data Processing: A Simulation Phantom Study

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