Study of the Mechanisms of Intracellular Oxidative Stress Initiated by Raman Laser in Cancer Cells of Hela Line at the Wavelength of 1265 Nm

Abstract

The dynamics of oxidative stress, DNA damage, changes in mitochondrial potential and mitochondrial mass are studied with the cancer cells of HELA line irradiated by a Raman laser at the wavelength of 1265 nm. It is demonstrated that Raman laser irradiation at this wavelength induces cell death causing an increase of the concentration of intracellular reactive oxygen species, an increase of DNA damage, and a decrease of mitochondrial potential and mitochondrial mass.