Study of the Efficacy and Safety of Contact Lens Used in Trabeculectomy

Abstract

Purpose. To investigate the efficacy and safety of soft bandage contact lens used in trabeculectomy. Methods. This was a prospective, randomized study which enrolled 200 glaucoma patients (200 eyes). Patients were randomized into Group 1, using contact lens after trabeculectomy, and Group 2, without contact lens. The primary outcome measurement was the comparison of success rates at 12 months after surgery. Qualified surgical success was defined as a postoperative intraocular pressure (IOP) value of 6–21 mmHg with or without topical antiglaucoma medication use at the last follow-up visit. Complete success was defined as the IOP between 6 and 21 mmHg without any antiglaucoma medication at the last follow-up visit. Postoperative data included IOP values, best-corrected visual acuity (BCVA), number of antiglaucoma medications, complications related to surgery, and bleb characteristics. Results. There were statistically significant differences between Groups 1 and 2 in mean IOP values at 3, 6, and 12 months after surgery (P<0.05). The 12-month life table rates for qualified surgical success were 94.7% and 86.3% in Groups 1 and 2, respectively (P=0.045). The 12-month life table rates for complete surgical success were 89.6% and 80.0% in Groups 1 and 2, respectively (P=0.042). At 12 months after surgery, the mean numbers of antiglaucoma medications were 0.3 ± 0.4 and 0.5 ± 0.6, respectively. (P=0.001). At the 12-month visit, the maximal bleb area was significantly different between groups (P=0.044), with Group 1 exhibiting a more diffused bleb area. Encysted blebs were observed in 7 (7%) eyes in Group 1 and 17 (17%) eyes in Group 2, with statistically significant differences (P=0.030). The 12-month life table rates for qualified surgical success were 94.7% (91 eyes) and 86.3% (82 eyes) in Groups 1 and 2, respectively (P=0.045). Conclusions. Bandage contact lens is a safe and effective device after fornix-based trabeculectomy.

A unique shape of scleral flap to increase surgical success rate in mitomycin C-augmented trabeculectomy: a 1-year study

“…These techniques included traditional single interrupted sutures at the end to conjunctival incision, edge purse-string sutures, or a suture with corneal grooves [12,23,24]. In our study, besides watertight sutures, we applied therapeutic soft contact lens to cover the conjunctival incisional wound to avoid bleb leakage and early hypotony according to previous studies [25][26][27][28][29]. This method may not only relieve wound discomfort to avoid eye blinking, but also prevent wound leaking to improve conjunctival healing.…”

Management of Dry Eye Disease in Asia: A Review

“…It has been shown to be effective in the treatment of neurotrophic keratitis, ocular chemical injury, and graft-versus-host disease [50]. Bandage lenses are also useful not only after corneal surgery but also after cataract surgery [51,52] and glaucoma surgery [53]. Therapeutic contact lenses for the treatment of DED have been particularly touted an alternate ophthalmic medication delivery system which increases medication residence time in the ocular, increases bioavailability, and allows for more convenient and effective treatment [54].…”

Treatment of Dry Eye Disease (DED) in Asia: Strategies for Short Tear Film Breakup Time-Type DED

“…It has been shown to be effective in the treatment of neurotrophic keratitis, ocular chemical injury, and graft-versus-host disease [60]. Bandage lenses are also useful not only after corneal surgery but also after cataract surgery [61,62] and glaucoma surgery [63]. Therapeutic contact lenses for the treatment of DED have been particularly touted an alternate ophthalmic medication delivery system which increases medication residence time in the ocular, increases bioavailability, and allows for more convenient and effective treatment [64].…”