Background: This study aims to introduce a modified method of trabeculectomy, and compare its effectiveness and safety to previous studies.Methods: Twenty-seven glaucoma patients (32 eyes) were admitted to Kaohsiung Veterans General Hospital to receive mitomycin-C augmented trabeculectomy with unique shape of scleral flap. The primary outcome measures were intraocular pressure (IOP) control and antiglaucoma medication use. Secondary outcome measures included: surgical success rate, complications, postoperative glaucoma surgical interventions, and lens extraction during the 1-year follow-up after trabeculectomy.Results: The IOP decreased significantly from baseline (28.80 ± 11.37 mm Hg) to postoperative day 1, week 1, week 2, week 4, week 6, month 3, month 6, and year 1 (range, 14.10 ± 5.90 to 17.80 ± 5.14 mm Hg; all p < 0.05). The antiglaucoma medication use also decreased significantly from baseline (n = 4.72 ± 1.25) to 1 year after trabeculectomy (n = 0.75 ± 1.37) (p < 0.001). During the 1-year follow-up period, neither surgical failure nor the requirement for glaucoma reoperation were observed. Early complications and interventions included bleb encapsulation (n = 3, 9.38%), bleb leaks (n = 3, 9.38%), and needling revision (n = 1, 3.13%). Late complications and interventions included bleb encapsulation (n = 2, 6.45%), needling (n = 5, 16.13%), and cataract extraction (n = 2, 6.45%).Conclusions: Our trabeculectomy method with a modified shape of scleral flap over anteriorized trap door to serve as safety valve yielded a favorable success rate and low hypotony-associated complication rate.
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